ArticleAntimicrobial agents and chemotherapy2020
Reconciling the Potentially Irreconcilable? Genotypic and Phenotypic Amoxicillin-Clavulanate Resistance in
Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Systematic review of wastewater surveillance of antimicrobial resistance in human populations.Environment international · 2022Pooled it
- Disinfection of hospital sink drains enriches pseudomonadota and efflux pump-mediated antibiotic resistance in reestablished biofilms.Nature communications · 2026Article
- Evaluation of a machine learning system for genomic antimicrobial susceptibility determination on a clinically representative test set.Microbiology spectrum · 2026Article
- Disinfection of Hospital Sink Drains Enriches Pseudomonadota and Efflux Pump-Mediated Antibiotic Resistance in Reestablished Biofilms.Research square · 2025Article
- Beyond the Spotlight:Antibiotics (Basel, Switzerland) · 2025Review
- Escherichia coli phylogeny drives co-amoxiclav resistance through variable expression of TEM-1 beta-lactamase.Nature communications · 2025Article
- An Evaluation of the ASTar Automated Antimicrobial Testing System for Gram-Negative Bacteria in Positive Blood Cultures.Antibiotics (Basel, Switzerland) · 2025Article
- Exploring uncatalogued genetic variation in antimicrobial resistance gene families in Escherichia coli: an observational analysis.The Lancet. Microbe · 2024Observational
- Amoxicillin-Clavulanate Breakpoints Against Enterobacterales: Rationale for Revision by the Clinical and Laboratory Standards Institute.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Article
- Genomic epidemiology of third-generation cephalosporin-resistantApplied and environmental microbiology · 2024Article
- Predictors of antibiogram performance and antibiotic resistance patterns in the northern Syrian region: A cross-sectional investigation.Exploratory research in clinical and social pharmacy · 2024Article
- Hound: a novel tool for automated mapping of genotype to phenotype in bacterial genomes assembled de novo.Briefings in bioinformatics · 2024Article
- Discordance between different bioinformatic methods for identifying resistance genes from short-read genomic data, with a focus onMicrobial genomics · 2023Article
- Molecular ecology of highest priority critically important antibiotic resistant Escherichia coli from mammals housed at an urban zoo.The Journal of antimicrobial chemotherapy · 2023Article
- Article
- Artificial Intelligence for Antimicrobial Resistance Prediction: Challenges and Opportunities towards Practical Implementation.Antibiotics (Basel, Switzerland) · 2023Review
- Genotypic resistance determined by whole genome sequencing versus phenotypic resistance in 234 Escherichia coli isolates.Scientific reports · 2023Article
- A longitudinal study reveals persistence of antimicrobial resistance on livestock farms is not due to antimicrobial usage alone.Frontiers in microbiology · 2023Article
- Canine Saliva as a Possible Source of Antimicrobial Resistance Genes.Antibiotics (Basel, Switzerland) · 2022Article
- Machine Learning for Antimicrobial Resistance Prediction: Current Practice, Limitations, and Clinical Perspective.Clinical microbiology reviews · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Resistance to amoxicillin-clavulanate, a widely used beta-lactam/beta-lactamase inhibitor combination antibiotic, is rising globally, and yet susceptibility testing remains challenging. To test whether whole-genome sequencing (WGS) could provide a more reliable assessment of susceptibility than traditional methods, we predicted resistance from WGS for 976
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.