Evidence map›Paper›PMID 32205344›Full record

ArticleAntimicrobial agents and chemotherapy2020

Telacebec for Ultrashort Treatment of Buruli Ulcer in a Mouse Model.

Deepak V Almeida, Paul J Converse, Till F Omansen, Sandeep Tyagi, Rokeya Tasneen, Jeongjun Kim, Eric L Nuermberger

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Article
  3. Buruli ulcer.Nature reviews. Disease primers · 2025
    Review
  4. The role of cytochrome bcNature communications · 2025
    Article
  5. Assessment of TB47 as a potential novel therapeutic agent:Antimicrobial agents and chemotherapy · 2025
    Article
  6. Life (Basel, Switzerland) · 2025
    Review
  7. Repurposing drugs to advance the treatment of Buruli ulcer.Antimicrobial agents and chemotherapy · 2025
    Article
  8. Article
  9. TargetingRSC medicinal chemistry · 2023
    Review
  10. The Many Hosts of Mycobacteria 9 (MHM9): A conference report.Tuberculosis (Edinburgh, Scotland) · 2023
    Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Deepak V AlmeidaCenter for Tuberculosis Research, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Paul J ConverseCenter for Tuberculosis Research, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Till F OmansenCenter for Tuberculosis Research, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Sandeep TyagiCenter for Tuberculosis Research, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Rokeya TasneenCenter for Tuberculosis Research, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Jeongjun KimQurient Co. Ltd., Seongnam, South Korea.
Eric L NuermbergerCenter for Tuberculosis Research, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA enuermb@jhmi.edu.
Johns Hopkins University · USQurient (South Korea) · KR

Funding

Closing the Gaps on Buruli Ulcer Diagnosis, Treatment, and PreventionR01AI113266 · NIAID · JOHNS HOPKINS UNIVERSITY · PI NUERMBERGER, ERIC L · 2016 to 2020
$4.4M
NIAID NIH HHS R01 AI113266
6 · The paper itself

Abstract

Telacebec (Q203) is a new antitubercular drug with extremely potent activity against

Indexed as

Buruli UlcerMycobacterium ulceransAnimalsAnti-Bacterial AgentsDrug Therapy, CombinationImidazolesMiceMice, Inbred BALB CPiperidinesPyridinesAnti-Bacterial AgentsImidazolesPiperidinesPyridinestelacebecBuruli ulcerMycobacterium ulceransQ203Telacebec

Identifiers

PMID32205344
PMCPMC7269501
OpenAlexW3011844850

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.