Evidence map›Paper›PMID 32205269›Full record

ArticleTravel medicine and infectious disease

Rapid viral diagnosis and ambulatory management of suspected COVID-19 cases presenting at the infectious diseases referral hospital in Marseille, France, - January 31st to March 1st, 2020: A respiratory virus snapshot.

Sophie Amrane, Hervé Tissot-Dupont, Barbara Doudier, Carole Eldin, Marie Hocquart, Morgane Mailhe, Pierre Dudouet, Etienne Ormières, Lucie Ailhaud, Philippe Parola and 11 more

Registry-linked trialAbstract read
In one paragraph

Article in Travel medicine and infectious disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04370262 (A Multi-site, Randomized, Double-Blind, Comparative Trial of the Safety and Efficacy of Standard of Care), which is not on this map. Cited by 71 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04370262 phase3completednot on this map

A Multi-site, Randomized, Double-Blind, Comparative Trial of the Safety and Efficacy of Standard of Care (SOC) Plus Famotidine vs SOC Plus Placebo for the Treatment of COVID-19 in Hospitalized Adults

TypeinterventionalSponsorNorthwell HealthRan2020 to 2020Enrolled233ConditionsCOVID-19ArmsSOC + Intravenous Famotidine, SOC + Placebo
3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  9. Control of common viral epidemics but not of SARS-CoV-2 through the application of hygiene and distancing measures.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2022
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  14. Review
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  18. Clinical outcomes in patients infected with different SARS-CoV-2 variants at one hospital during three phases of the COVID-19 epidemic in Marseille, France.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2021
    Article
  19. Clinical outcomes in COVID-19 patients infected with different SARS-CoV-2 variants in Marseille, France.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2021
    Article
  20. Mouth Washing Impaired SARS-CoV-2 Detection in Saliva.Diagnostics (Basel, Switzerland) · 2021
    Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Sophie AmraneIHU-Méditerranée Infection, Marseille, France; Aix Marseille Univ, IRD, APHM, MEPHI, Marseille, France.
Hervé Tissot-DupontIHU-Méditerranée Infection, Marseille, France; Aix Marseille Univ, IRD, APHM, MEPHI, Marseille, France.
Barbara DoudierIHU-Méditerranée Infection, Marseille, France.
Carole EldinIHU-Méditerranée Infection, Marseille, France; Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.
Marie HocquartIHU-Méditerranée Infection, Marseille, France.
Morgane MailheIHU-Méditerranée Infection, Marseille, France.
Pierre DudouetIHU-Méditerranée Infection, Marseille, France.
Etienne OrmièresIHU-Méditerranée Infection, Marseille, France.
Lucie AilhaudIHU-Méditerranée Infection, Marseille, France.
Philippe ParolaIHU-Méditerranée Infection, Marseille, France; Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.
Jean-Christophe LagierIHU-Méditerranée Infection, Marseille, France; Aix Marseille Univ, IRD, APHM, MEPHI, Marseille, France.
Philippe BrouquiIHU-Méditerranée Infection, Marseille, France; Aix Marseille Univ, IRD, APHM, MEPHI, Marseille, France.
Christine ZandottiIHU-Méditerranée Infection, Marseille, France; Aix-Marseille Univ, APHM, Unité des Virus Émergents (UVE), IRD 190 - Inserm 1207, Marseille, France.
Laetitia NinoveIHU-Méditerranée Infection, Marseille, France; Aix-Marseille Univ, APHM, Unité des Virus Émergents (UVE), IRD 190 - Inserm 1207, Marseille, France.
Léa LucianiIHU-Méditerranée Infection, Marseille, France; Aix-Marseille Univ, APHM, Unité des Virus Émergents (UVE), IRD 190 - Inserm 1207, Marseille, France.
Céline BoschiIHU-Méditerranée Infection, Marseille, France.
Bernard La ScolaIHU-Méditerranée Infection, Marseille, France; Aix Marseille Univ, IRD, APHM, MEPHI, Marseille, France.
Didier RaoultIHU-Méditerranée Infection, Marseille, France; Aix Marseille Univ, IRD, APHM, MEPHI, Marseille, France.
Matthieu MillionIHU-Méditerranée Infection, Marseille, France; Aix Marseille Univ, IRD, APHM, MEPHI, Marseille, France.
Philippe ColsonIHU-Méditerranée Infection, Marseille, France; Aix Marseille Univ, IRD, APHM, MEPHI, Marseille, France.
Philippe GautretIHU-Méditerranée Infection, Marseille, France; Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France. Electronic address: philippe.gautret@ap-hm.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRapid virological diagnosis is needed to limit the length of isolation for suspected COVID-19 cases.

methodWe managed the first 280 patients suspected to have COVID-19 through a rapid care circuit and virological diagnosis in our infectious disease reference hospital in Marseille, France. Rapid viral detection was performed on sputum and nasopharyngeal samples.

resultsOver our study period, no SARS-CoV-2 was detected. Results were obtained within approximately 3 h of the arrival of patient samples at the laboratory. Other viral infections were identified in 49% of the patients, with most common pathogens being influenza A and B viruses, rhinovirus, metapneumovirus and common coronaviruses, notably HKU1 and NL63.

conclusionEarly recognition of COVID-19 is critical to isolate confirmed cases and prevent further transmission. Early rule-out of COVID-19 allows public health containment measures to be adjusted by reducing the time spent in isolation.

Indexed as

BetacoronavirusClinical Laboratory TechniquesAdolescentAdultAgedAged, 80 and overChildChild, PreschoolCoronavirus InfectionsCOVID-19COVID-19 TestingDiagnosis, DifferentialFemaleFranceHumansInfantCoronavirusesCOVID-19EpidemicInfluenzaSARS-CoV-2Travel

Identifiers

PMID32205269
PMCPMC7102626

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.