ArticleClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2021
Normal Functional Luminal Imaging Probe Panometry Findings Associate With Lack of Major Esophageal Motility Disorder on High-Resolution Manometry.
Article in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 50 citations in OpenAlex.
- Utilization trends for esophageal motility testing in the United States.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2026Article
- Accuracy of Novice Raters for Esophageal Motility Classifications Using Functional Lumen Imaging Probe Panometry.Neurogastroenterology and motility · 2026Article
- The Role of Functional Lumen Imaging Probe (FLIP) in Addition to High-Resolution Manometry and Timed Barium Esophagram in Treated Achalasia Patients With Persistent or Recurrent Symptoms.Neurogastroenterology and motility · 2026Observational
- Artificial Intelligence and FLIP Panometry-Automated Classification of Esophageal Motility Patterns.Journal of clinical medicine · 2026Article
- Eosinophilic oesophagitis: pathophysiology, diagnosis, and treatment.BMJ medicine · 2026Review
- A combined endoscopy and functional lumen imaging probe panometry approach can expedite diagnosis of esophageal motility disorders.Gastrointestinal endoscopy · 2025Article
- Can intraoperative impedance planimetry (EndoFLIP™) during anti-reflux surgery replace preoperative manometry with no difference in patient outcomes?Surgical endoscopy · 2025Article
- Functional Lumen Imaging Probe Panometry.Gastrointestinal endoscopy clinics of North America · 2025Review
- A Standardized Approach to Performing and Interpreting Functional Lumen Imaging Probe Panometry for Esophageal Motility Disorders: The Dallas Consensus.Gastroenterology · 2025Article
- The Esophageal Response to Distension on Functional Lumen Imaging Probe Panometry Is Minimally Changed by Conscious Sedation in Healthy Asymptomatic Subjects.Journal of neurogastroenterology and motility · 2025Article
- Impedance planimetry and panometry (EndoFLIP™) can replace manometry in preoperative anti-reflux surgery assessment.Surgical endoscopy · 2024Article
- The impact of primary peristalsis, contractile reserve, and secondary peristalsis on esophageal clearance measured by timed barium esophagogram.Neurogastroenterology and motility · 2023Article
- The Use of Intraoperative Esophageal Functional Luminal Imaging Probe for Prediction of Therapeutic Outcomes in Achalasia Patients.Journal of neurogastroenterology and motility · 2023Article
- An artificial intelligence platform provides an accurate interpretation of esophageal motility from Functional Lumen Imaging Probe Panometry studies.Neurogastroenterology and motility · 2023Article
- Estimating Probability for Esophageal Obstruction: A Diagnostic Decision Support Tool Applying Machine Learning to Functional Lumen Imaging Probe Panometry.Journal of neurogastroenterology and motility · 2022Article
- Validation of Clinically Relevant Thresholds of Esophagogastric Junction Obstruction Using FLIP Panometry.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2022Article
- Devices for esophageal function testing.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2022Article
- Validation of secondary peristalsis classification using FLIP panometry in 741 subjects undergoing manometry.Neurogastroenterology and motility · 2022Article
- The impact of pneumoperitoneum on esophagogastric junction distensibility during anti-reflux surgery.Surgical endoscopy · 2022Article
- Dysphagia: Novel and Emerging Diagnostic Modalities.Gastroenterology clinics of North America · 2021Review
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
BACKGROUND &
aimsA normal esophageal response to distension on functional luminal imaging probe (FLIP) panometry during endoscopy might indicate normal esophageal motor function. We aimed to investigate the correlation of normal FLIP panometry findings with esophageal high-resolution manometry (HRM) and outcomes of discrepant patients.
methodsWe performed a retrospective study using data from a registry of patients who completed FLIP during sedated endoscopy. We identified 111 patients with normal FLIP panometry findings (mean age, 42 y; 69% female) and corresponding HRM data. A normal FLIP panometry was defined as an esophagogastric junction (EGJ) distensibility index greater than 3.0 mm
resultsHRM results were classified as normal motility in 78 patients (70%), ineffective esophageal motility in 10 patients (9%), EGJ outflow obstruction in 20 patients (18%), and 3 patients (3%) as other. In patients with EGJ outflow obstruction based on HRM, the integrated relaxation pressure normalized on adjunctive swallows in 16 of 20 patients (80%), and in 8 of 9 patients (88%) who completed a barium esophagram and had normal barium clearance. Thus, although 23 of 111 patients (21%) with normal FLIP panometry had abnormal HRM findings, these HRMs often were considered to be false-positive or equivocal results. All patients with an abnormal result from HRM were treated conservatively.
conclusionsIn a retrospective cohort study, we found that patients with normal FLIP panometry results did not have a clinical impression of a major esophageal motor disorder. Normal FLIP panometry results can exclude esophageal motility disorders at the time of endoscopy, possibly negating the need for HRM in select patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.