ReviewVirus research2020
Maize lethal necrosis (MLN): Efforts toward containing the spread and impact of a devastating transboundary disease in sub-Saharan Africa.
Review in Virus research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 94 citations in OpenAlex.
- Introgression of QTL hotspot regions enhances grain yield and maize lethal necrosis resistance in elite maize lines.Scientific reports · 2026Article
- Targeted knockout of a host peroxisomal peptidase confers field resistance to maize lethal necrosis.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Yield and combining ability of temperate ex-PVP introgressed and tropical maize under contrasting moisture regimes.PloS one · 2026Article
- Breeding climate-resilient maize for food security in semi-arid sub-Saharan Africa: strategies and future directions.Frontiers in plant science · 2026Review
- Single and dual RPA-CRISPR/Cas assays for point-of-need detection of Stewart's wilt pathogen (Pantoea stewartii subsp. stewartii) of corn and Maize dwarf mosaic virus.Pest management science · 2025Article
- Global Transcriptomic Analysis of Inbred Lines Reveal Candidate Genes for Response to Maize Lethal Necrosis.Plants (Basel, Switzerland) · 2025Article
- Africa and zero hunger agenda: genome editing policy landscape, challenges and opportunities.Frontiers in bioengineering and biotechnology · 2025Review
- Genetic analysis of ear, husk, and tassel traits in tropical maize under diverse environments.Frontiers in plant science · 2025Article
- Genome editing in Sub-Saharan Africa: a game-changing strategy for climate change mitigation and sustainable agriculture.GM crops & food · 2024Review
- Ms44-SPT: unique genetic technology simplifies and improves hybrid maize seed production in sub-Saharan Africa.Scientific reports · 2024Article
- Edited eukaryotic translation initiation factors confer resistance against maize lethal necrosis.Plant biotechnology journal · 2024Article
- Development of nanobodies against the coat protein of maize chlorotic mottle virus.FEBS open bio · 2024Article
- A combination of joint linkage and genome-wide association study reveals putative candidate genes associated with resistance to northern corn leaf blight in tropical maize.Frontiers in plant science · 2024Article
- Deep learning models for the early detection of maize streak virus and maize lethal necrosis diseases in Tanzania.Frontiers in artificial intelligence · 2024Article
- Inheritance of resistance to maize lethal necrosis in tropical maize inbred lines.Frontiers in plant science · 2024Article
- Major biotic stresses affecting maize production in Kenya and their implications for food security.PeerJ · 2023Review
- Genetic trends for yield and key agronomic traits in pre-commercial and commercial maize varieties between 2008 and 2020 in Uganda.Frontiers in plant science · 2023Article
- Discovery of genomic regions associated with grain yield and agronomic traits in Bi-parental populations of maize (Frontiers in genetics · 2023Article
- Effects of Poty-Potexvirus Synergism on Growth, Photosynthesis and Metabolite Status ofViruses · 2022Article
- Review
Corrections and comments
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Authors and funding
18 authors at 8 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Maize lethal necrosis (MLN), a complex viral disease, emerged as a serious threat to maize production and the livelihoods of smallholders in eastern Africa since 2011, primarily due to the introduction of maize chlorotic mottle virus (MCMV). The International Maize and Wheat Improvement Center (CIMMYT), in close partnership with national and international partners, implemented a multi-disciplinary and multi-institutional strategy to curb the spread of MLN in sub-Saharan Africa, and mitigate the impact of the disease. The strategy revolved around a) intensive germplasm screening and fast-tracked development and deployment of MLN-tolerant/resistant maize hybrids in Africa-adapted genetic backgrounds; b) optimizing the diagnostic protocols for MLN-causing viruses, especially MCMV, and capacity building of relevant public and private sector institutions on MLN diagnostics and management; c) MLN monitoring and surveillance across sub-Saharan Africa in collaboration with national plant protection organizations (NPPOs); d) partnership with the private seed sector for production and exchange of MLN pathogen-free commercial maize seed; and e) awareness creation among relevant stakeholders about MLN management, including engagement with policy makers. The review concludes by highlighting the need to keep continuous vigil against MLN-causing viruses, and preventing any further spread of the disease to the major maize-growing countries that have not yet reported MLN in sub-Saharan Africa.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.