Evidence map›Paper›PMID 32204561›Full record

ArticleMedicines (Basel, Switzerland)2020

Severe Neutropenia and Agranulocytosis Related to Antithyroid Drugs: A Study of 30 Cases Managed in A Single Reference Center.

Emmanuel Andrès, Noel Lorenzo Villalba, Rachel Mourot-Cottet, Frédéric Maloisel, Martine Tebacher, Jacques-Eric Gottenberg, Bernard Goichot, Raoul Herbrecht, Abrar-Ahmad Zulfiqar

Open access · goldAbstract read
In one paragraph

Article in Medicines (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Emmanuel AndrèsDepartments of Internal Medicine, Strasbourg University Hospitals, 67000 Strasbourg, France.
Noel Lorenzo VillalbaDepartments of Internal Medicine, Strasbourg University Hospitals, 67000 Strasbourg, France.
Rachel Mourot-CottetDepartments of Internal Medicine, Strasbourg University Hospitals, 67000 Strasbourg, France.
Frédéric MaloiselOnco-Hematology, Strasbourg University Hospitals, 67000 Strasbourg, France.
Martine TebacherRegional Pharmacovigilance Centre of Alsace, 67000 Strasbourg, France.
Jacques-Eric GottenbergRheumatology, Strasbourg University Hospitals, 67000 Strasbourg, France.
Bernard GoichotDepartments of Internal Medicine, Strasbourg University Hospitals, 67000 Strasbourg, France.
Raoul HerbrechtOnco-Hematology, Strasbourg University Hospitals, 67000 Strasbourg, France.
Abrar-Ahmad ZulfiqarDepartments of Internal Medicine, Strasbourg University Hospitals, 67000 Strasbourg, France.
Université de Strasbourg · FRObservatoire Régional de la Santé d’Alsace · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe most important series devoted to antithyroid drug-induced severe neutropenia and agranulocytosis are Japanese studies, almost specifically in relation to the intake of methimazole. The clinical data of 30 Caucasian patients followed up for antithyroid drug-induced neutropenia at a third-level hospital are reported.

Indexed as

agranulocytosisantithyroid drugcarbimazolediagnosisfevergranulocyte colony-stimulating factorhematopoietic growth factorinfectionneutropeniapropylthiouracil

Identifiers

PMID32204561
PMCPMC7151575
OpenAlexW3011989234

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.