ReviewNutrients2020
Nutrition and the Immune System: A Complicated Tango.
Review in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
114 citing papers in PubMed, 2 syntheses or guidelines pooled it, 235 citations in OpenAlex.
- The Impact of the Alternate Mediterranean Diet (aMED) on the Prevention of Chronic Liver Disease: A Meta-Analysis of Observational Studies.Nutrients · 2025Pooled it
- Dietary Interventions with or without Omega-3 Supplementation for the Management of Rheumatoid Arthritis: A Systematic Review.Nutrients · 2021Pooled it
- Trial
- Effects of the Traditional Mediterranean Diet in Patients with Otitis Media with Effusion.Nutrients · 2021Trial
- The FINE Index: A Frailty- and Immunonutrition-Based Nomogram for Survival in Geriatric Breast Cancer: A Retrospective Study.Cancer medicine · 2026Article
- Article
- Article
- The association between dietary inflammatory index and latent tuberculosis infection: Confounding role of country of birth.Clinics (Sao Paulo, Brazil) · 2026Article
- Daily Consumption of Unprocessed/Minimally Processed Foods and Its Relationship with Serum Phosphorus, CD3+, and CD45+ Cell Counts in People Living with HIV: A Cross-Sectional Descriptive Study.Medical sciences (Basel, Switzerland) · 2026Article
- The Geriatric Nutritional Risk Index and its association with all-cause mortality in cancer patients with sepsis: a dual-center retrospective cohort study.Frontiers in nutrition · 2026Article
- Avocado consumption during pregnancy linked to lower child food allergy risk: prospective KuBiCo study.Pediatric research · 2026Article
- Nutritional, antioxidant, and sensory properties of Ziziphus spina-christi fruit powder and its application in bakery products.Scientific reports · 2025Article
- Special Issue: Diet and Lifestyle Factors Associated with Allergic Diseases in Early Life.Nutrients · 2025Article
- Feeding the Skin Barrier: The Impact of Macro- and Micronutrients on Skin Barrier Function.Clinical and translational allergy · 2025Review
- Autoimmune Gastritis andInternational journal of molecular sciences · 2025Review
- Chlorogenic acid alters ileal microbiota and metabolites in broiler chickens under immune stress.Microbiology spectrum · 2025Article
- Molecular Mechanisms and Clinical Implications of Complex Prehabilitation in Colorectal Cancer Surgery: A Comprehensive Review.International journal of molecular sciences · 2025Review
- Risk factors and predictive thresholds for postoperative pleural effusion in children with neuroblastoma: a retrospective cohort study.World journal of surgical oncology · 2025Article
- Contribution to the debate on the origin of autoimmune joint diseases in Europe through an archaeological case of still's disease.Scientific reports · 2025Article
- Review
54 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Enthusiasm exists for the potential of diet to impact the immune system, prevent disease and its therapeutic potential. Herein, we describe the challenge to nutrition scientists in defining this relationship through case studies of diets and nutrients in the context of allergic and autoimmune diseases. Moderate-quality evidence exists from both human intervention and observational studies to suggest that diet and individual nutrients can influence systemic markers of immune function and inflammation; numerous challenges exist for demonstrating the impact of defined diets and nutrient interventions on clearly influencing immune-mediated-clinical disease endpoints. A growing body of evidence suggests that further consideration of dietary patterns, immune system and gut microbiome composition and function, and subsequent epigenetic modifications are needed to improve our understanding of diet-immune system interactions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.