Evidence map›Paper›PMID 32204466›Full record

ArticleBiomedicines2020

Identification of Aberrantly-Expressed Long Non-Coding RNAs in Osteoblastic Cells from Osteoporotic Patients.

Federica Centofanti, Massimo Santoro, Mario Marini, Virginia Veronica Visconti, Anna Maria Rinaldi, Monica Celi, Giovanna D'Arcangelo, Giuseppe Novelli, Augusto Orlandi, Virginia Tancredi and 2 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. The Roles ofGenes · 2022
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Long Noncoding RNAFrontiers in cell and developmental biology · 2021
    Review
  13. Review
  14. Review
  15. Identification of New Potential LncRNA Biomarkers in Hirschsprung Disease.International journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Federica CentofantiDepartment of Biomedicine and Prevention, Anatomic Pathology Section, University of Rome "Tor Vergata", 00133 Rome, Italy.
Massimo SantoroIRCCS Don Gnocchi Foundation, 20121 Milan, Italy.ORCID 0000-0002-3037-2775
Mario MariniDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Virginia Veronica ViscontiDepartment of Biomedicine and Prevention, Medical Genetics Section, University of Rome "Tor Vergata", 00133 Rome, Italy.
Anna Maria RinaldiDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Monica CeliDepartment of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Giovanna D'ArcangeloDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Giuseppe NovelliDepartment of Biomedicine and Prevention, Medical Genetics Section, University of Rome "Tor Vergata", 00133 Rome, Italy.
Augusto OrlandiDepartment of Biomedicine and Prevention, Anatomic Pathology Section, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0001-7202-5854
Virginia TancrediDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0003-4779-2212
Umberto TarantinoDepartment of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Annalisa BottaDepartment of Biomedicine and Prevention, Medical Genetics Section, University of Rome "Tor Vergata", 00133 Rome, Italy.
University of Rome Tor Vergata · ITDon Carlo Gnocchi Foundation · IT

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca 201528E7CM
6 · The paper itself

Abstract

Osteoporosis (OP) is a multifactorial disease influenced by genetic, epigenetic, and environmental factors. One of the main causes of the bone homeostasis alteration is inflammation resulting in excessive bone resorption. Long non-coding RNAs (lncRNAs), have a crucial role in regulating many important biological processes in bone, including inflammation. We designed our study to identify lncRNAs misregulated in osteoblast primary cultures derived from OP patients (

Indexed as

bone homeostasisepigeneticsinflammationlong non-coding RNAsosteoblastosteoporosis

Identifiers

PMID32204466
PMCPMC7148473
OpenAlexW3012382244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.