Evidence map›Paper›PMID 32204420›Full record

ReviewMolecules (Basel, Switzerland)2020

Targeting the Inositol Pyrophosphate Biosynthetic Enzymes in Metabolic Diseases.

Sandip Mukherjee, Jake Haubner, Anutosh Chakraborty

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
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  14. Synthesis and biological evaluation of flavonoid-based IP6K2 inhibitors.Journal of enzyme inhibition and medicinal chemistry · 2023
    Article
  15. Article
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  17. Review
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  19. Article
  20. Whole BodyInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sandip MukherjeeDepartment of Pharmacology and Physiology, Saint Louis University School of Medicine, Saint Louis, MO 63104, USA.
Jake HaubnerDepartment of Pharmacology and Physiology, Saint Louis University School of Medicine, Saint Louis, MO 63104, USA.
Anutosh ChakrabortyDepartment of Pharmacology and Physiology, Saint Louis University School of Medicine, Saint Louis, MO 63104, USA.
Saint Louis University · US

Funding

Inositol hexakisphosphate kinase-1 As a Novel Target in ObesityR01DK103746 · NIDDK · SCRIPPS FLORIDA · PI CHAKRABORTY, ANUTOSH · 2015 to 2019
$1.9M
NIDDK NIH HHS R01DK103746
6 · The paper itself

Abstract

In mammals, a family of three inositol hexakisphosphate kinases (IP6Ks) synthesizes the inositol pyrophosphate 5-IP7 from IP6. Genetic deletion of

Indexed as

AnimalsEnergy MetabolismEnzyme InhibitorsHumansInositol PhosphatesMetabolic DiseasesMiceMolecular Targeted TherapyPhosphotransferases (Phosphate Group Acceptor)Phytic AcidEnzyme Inhibitorsinositol heptakisphosphateInositol PhosphatesPhosphotransferases (Phosphate Group Acceptor)Phytic Acid5-IP7diabetesIP6IP6KNAFLobesity

Identifiers

PMID32204420
PMCPMC7144392
OpenAlexW3011487813

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.