ArticleMolecules (Basel, Switzerland)2020
Chemopreventive and Therapeutic Efficacy of
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In one paragraph
Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 3 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 3 pooled it
3.6field-weighted citation impact, top 6% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 3 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- Uncharted phytochemical frontiers: a systematic review of novel bioactive compounds from underexplored aromatic plants for cancer therapy.Frontiers in oncology · 2026Pooled it
- Therapy-resistant breast cancer in focus: Clinically relevant mitigation by flavonoids targeting cancer stem cells.Frontiers in pharmacology · 2023Pooled it
- Research Status and Hotspots of Anticancer Natural Products Based on the Patent Literature and Scientific Articles.Frontiers in pharmacology · 2022Pooled it
- Natural Plant Bioactives as Regulators of Histone Modifications: Bridging Epigenetics and Anticancer Therapy.Phytotherapy research : PTR · 2026Review
- Regulation of long non-coding RNAs by essential oils: Therapeutic implications in human diseases.Genetics and molecular biology · 2026Article
- Exploring the molecular mechanism of Coptis-cinnamon in combating gastric cancer via the MAPK Pathway based on network pharmacology.Frontiers in oncology · 2026Article
- Microglial Inflammatory Response in the Glioblastoma Microenvironment in Preclinical Models.Molecular neurobiology · 2025Article
- Emerging phytochemical-based nanocarriers: redefining the perspectives of breast cancer therapy.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- Comprehensive Phytochemical Analysis and Evaluation of Antioxidant, Antimicrobial, Cytotoxic, and Immunomodulatory Activities of Commercial Cinnamon Bark Essential Oil (International journal of molecular sciences · 2025Article
- Natural anticancer agents: prospection of medicinal and aromatic plants in modern chemoprevention and chemotherapy.Natural products and bioprospecting · 2025Review
- Integrative approach to decipher pharmacological mechanism of Cinnamomum zeylanicum essential oil in prostate cancer.Medical oncology (Northwood, London, England) · 2025Article
- γCyclodextrin-assisted Aqueous Extract of Cinnamon for Cancer and Stress Management.Current topics in medicinal chemistry · 2025Article
- Chemopreventive and therapeutic effects ofFrontiers in pharmacology · 2025Article
- Investigation of Uncovering Molecular Mechanisms of Alcohol-Induced Female Infertility-A Rational Approach.Reproductive sciences (Thousand Oaks, Calif.) · 2024Review
- Cinnamaldehyde: Pharmacokinetics, anticancer properties and therapeutic potential (Review).Molecular medicine reports · 2024Review
- Spicing Up Meat Preservation:Foods (Basel, Switzerland) · 2024Review
- Investigation of Antihypertensive Properties of Chios Mastic via Monitoring microRNA-21 Expression Levels in the Plasma of Well-Controlled Hypertensive Patients.Non-coding RNA · 2024Article
- An in vitro study elucidating the synergistic effects of aqueous cinnamon extract and an anti-TNF-α biotherapeutic: implications for a complementary and alternative therapy for non-responders.BMC complementary medicine and therapies · 2024Article
- Cell plasticity modulation by flavonoids in resistant breast carcinoma targeting the nuclear factor kappa B signaling.Cancer metastasis reviews · 2024Review
- Significance of flavonoids targeting PI3K/Akt/HIF-1α signaling pathway in therapy-resistant cancer cells - A potential contribution to the predictive, preventive, and personalized medicine.Journal of advanced research · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors at 6 institutions in 4 countries.
Peter KubatkaDepartment of Medical Biology, Jessenius Faculty of Medicine, Comenius University in Bratislava, 03601 Martin, Slovakia.ORCID 0000-0003-4312-5076
Martin KelloDepartment of Pharmacology, Faculty of Medicine, P. J. Šafarik University, 040 11 Košice, Slovakia.ORCID 0000-0002-2454-5799
Karol KajoSt. Elisabeth Oncology Institute, Department of Pathology, 812 50 Bratislava, Slovakia.
Marek SamecDepartment of Obstetrics and Gynecology, Jessenius Faculty of Medicine, Comenius University in Bratislava, 036 01 Martin, Slovakia.
Karin JasekDivision of Oncology, Biomedical Center Martin, Comenius University in Bratislava, Jessenius Faculty of Medicine, 036 01 Martin, Slovakia.
Desanka VybohovaDepartment of Anatomy, Jessenius Faculty of Medicine, Comenius University in Bratislava, 036 01 Martin, Slovakia.
Sona UramovaDivision of Oncology, Biomedical Center Martin, Comenius University in Bratislava, Jessenius Faculty of Medicine, 036 01 Martin, Slovakia.
Alena LiskovaDepartment of Obstetrics and Gynecology, Jessenius Faculty of Medicine, Comenius University in Bratislava, 036 01 Martin, Slovakia.
Vladimira SadlonovaDepartment of Microbiology and Immunology, Jessenius Faculty of Medicine, Comenius University in Bratislava, 036 01 Martin, Slovakia.
Lenka KoklesovaDepartment of Obstetrics and Gynecology, Jessenius Faculty of Medicine, Comenius University in Bratislava, 036 01 Martin, Slovakia.
Radovan MurinDepartment of Biochemistry, Jessenius Faculty of Medicine, Comenius University in Bratislava, 036 01 Martin, Slovakia.ORCID 0000-0002-2952-0398
Marian AdamkovDepartment of Histology and Embryology, Jessenius Faculty of Medicine, Comenius University in Bratislava, 036 01 Martin, Slovakia.
Karel SmejkalDepartment of Natural Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences, 612 42 Brno, Czech Republic.ORCID 0000-0002-4336-7924
Emil SvajdlenkaDepartment of Natural Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences, 612 42 Brno, Czech Republic.
Peter SolarDepartment of Medical Biology, Faculty of Medicine, P. J. Safarik University, 04011 Kosice, Slovakia.ORCID 0000-0002-1287-2979
Samson Mathews SamuelWeill Cornell Medicine in Qatar, Qatar Foundation-Education City, 24144 Doha, Qatar.ORCID 0000-0002-5541-6623
Monika KassayovaDepartment of Animal Physiology, Institute of Biology and Ecology, Faculty of Science, P. J. Šafarik University, 04001 Košice, Slovakia.
Taeg Kyu KwonDepartment of Immunology and School of Medicine, Keimyung University, Dalseo-Gu, 42601 Daegu, Korea.ORCID 0000-0003-1204-2059
Pavol ZuborOBGY Health & Care, Ltd., 01001 Zilina, Slovakia.
Martin PecDepartment of Medical Biology, Jessenius Faculty of Medicine, Comenius University in Bratislava, 03601 Martin, Slovakia.
Jan DankoDepartment of Obstetrics and Gynecology, Jessenius Faculty of Medicine, Comenius University in Bratislava, 036 01 Martin, Slovakia.
Dietrich BüsselbergWeill Cornell Medicine in Qatar, Qatar Foundation-Education City, 24144 Doha, Qatar.ORCID 0000-0001-5196-3366
Jan MojzisDepartment of Pharmacology, Faculty of Medicine, P. J. Šafarik University, 040 11 Košice, Slovakia.
Comenius University Bratislava · SKUniversity of Pavol Jozef Šafárik · SKUniversity of Veterinary Sciences Brno · CZWeill Cornell Medical College in Qatar · QABiomedical Research Center of the Slovak Academy of Sciences · SKKeimyung University · KR
Funding
Agentúra na Podporu Výskumu a Vývoja APVV-16-0021 and APVV-16-0446"CENTER OF EXCELLENCE FOR RESEARCH IN PERSONALIZED THERAPY (CEVYPET)", ITMS: 26220120053"Medicínsky univerzitný vedecký park v Košiciach (MediPark, Košice - Fáza II.)", code ITMS2014 + 313011D103Vedecká Grantová Agentúra MŠVVaŠ SR a SAV 1/0136/19, 1/0653/19, and 1/0753/17
Abstract
Comprehensive oncology research suggests an important role of phytochemicals or whole plant foods in the modulation of signaling pathways associated with anticancer action. The goal of this study is to assess the anticancer activities of
Indexed as
AnimalsAntineoplastic Agents, PhytogenicBreast NeoplasmsCell Line, TumorCell ProliferationCell SurvivalCinnamomum zeylanicumDose-Response Relationship, DrugFemaleHistonesHumansMCF-7 CellsMiceMicroRNAsOils, VolatilePlant BarkAntineoplastic Agents, PhytogenicHistonesMicroRNAsOils, VolatilePlant Oilsapoptosiscancer stem cellscell proliferationCinnamomum zeylanicumepigeneticsmammary carcinogenesisMCF-7 cellsMDA-MB-231 cellsmousepreventive medicinerat
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.