ReviewThe Lancet. Respiratory medicine2020
Planning and provision of ECMO services for severe ARDS during the COVID-19 pandemic and other outbreaks of emerging infectious diseases.
Review in The Lancet. Respiratory medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 273 papers, 9 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
273 citing papers in PubMed, 9 syntheses or guidelines pooled it, 548 citations in OpenAlex.
- Does COVID-19 vaccination affect risk perception and adherence to preventive behaviors? A systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Comparison of venovenous extracorporeal membrane oxygenation, prone position and supine mechanical ventilation for severely hypoxemic acute respiratory distress syndrome: a network meta-analysis.Intensive care medicine · 2024Pooled it
- Higher Risk of Acute Respiratory Distress Syndrome and Risk Factors among Patients with COVID-19: A Systematic Review, Meta-Analysis and Meta-Regression.International journal of environmental research and public health · 2022Pooled it
- Evolving outcomes of extracorporeal membrane oxygenation during the first 2 years of the COVID-19 pandemic: a systematic review and meta-analysis.Critical care (London, England) · 2022Pooled it
- Integrative omics provide biological and clinical insights into acute respiratory distress syndrome.Intensive care medicine · 2021Pooled it
- Extracorporeal membrane oxygenation for COVID-19: a systematic review and meta-analysis.Critical care (London, England) · 2021Pooled it
- Guideline
- Management of hospitalised adults with coronavirus disease 2019 (COVID-19): a European Respiratory Society living guideline.The European respiratory journal · 2021Guideline
- Adult cardiovascular surgery and the coronavirus disease 2019 (COVID-19) pandemic: the Italian experience.Interactive cardiovascular and thoracic surgery · 2020Pooled it
- Pre-cannulation ventilation duration and the trajectory of venovenous extracorporeal membrane oxygenation in COVID-19-related acute respiratory distress syndrome: a nationwide competing-risks cohort study.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2026Article
- Outcome of Emergency Pulmonary Lobectomy under ECMO Support in Patients with COVID-19.The Thoracic and cardiovascular surgeon · 2026Article
- Decision-making and institutional support for ECMO and ventilator allocation during the COVID-19 pandemic: a nationwide cross-sectional survey of designated physicians at Japan's advanced critical care and emergency centers.BMC medical ethics · 2026Article
- rECMOmender: Reinforcement Learning for Decision Support in Venovenous Extracorporeal Membrane Oxygenation Management.Critical care explorations · 2026Article
- Magnetostaltic pumping in an ex vivo extracorporeal membrane oxygenation model.Journal of translational medicine · 2026Article
- The ethics of blood stewardship and quantitative futility assessments to predict certain death in neurotrauma patients.Frontiers in medicine · 2026Review
- Prevalence and microbiological profile of septic complications following ECMO decannulation: a prospective single-center study.Scientific reports · 2025Article
- Frailty and outcomes after extracorporeal membrane oxygenation: a binational registry-based cohort study.Critical care (London, England) · 2025Article
- Frontliners narratives: qualitative insights into EMDR group therapy during COVID-19.European journal of psychotraumatology · 2025Article
- Interleukin-6-to-lymphocyte count ratio in the prognosis of moderate-to-severe acute respiratory distress syndrome supported by venovenous extracorporeal membrane oxygenation: a single-center retrospective study.Journal of thoracic disease · 2025Article
- Multicultural ethics in crisis: prioritizing ECMO allocation and the role of critical consciousness.International journal for equity in health · 2025Article
213 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
9 authors at 8 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
WHO interim guidelines recommend offering extracorporeal membrane oxygenation (ECMO) to eligible patients with acute respiratory distress syndrome (ARDS) related to coronavirus disease 2019 (COVID-19). The number of patients with COVID-19 infection who might develop severe ARDS that is refractory to maximal medical management and require this level of support is currently unknown. Available evidence from similar patient populations suggests that carefully selected patients with severe ARDS who do not benefit from conventional treatment might be successfully supported with venovenous ECMO. The need for ECMO is relatively low and its use is mostly restricted to specialised centres globally. Providing complex therapies such as ECMO during outbreaks of emerging infectious diseases has unique challenges. Careful planning, judicious resource allocation, and training of personnel to provide complex therapeutic interventions while adhering to strict infection control measures are all crucial components of an ECMO action plan. ECMO can be initiated in specialist centres, or patients can receive ECMO during transportation from a centre that is not specialised for this procedure to an expert ECMO centre. Ensuring that systems enable safe and coordinated movement of critically ill patients, staff, and equipment is important to improve ECMO access. ECMO preparedness for the COVID-19 pandemic is important in view of the high transmission rate of the virus and respiratory-related mortality.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.