ArticlePLoS biology2020
CsIVP functions in vasculature development and downy mildew resistance in cucumber.
Article in PLoS biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 56 citations in OpenAlex.
- Review
- Genomics assisted breeding for mildew resistance in cucumber: from gene discovery to future innovations.Plant molecular biology · 2026Review
- Article
- Genetic Insights and Molecular Breeding Approaches for Downy Mildew Resistance in Cucumber (International journal of molecular sciences · 2024Review
- CsWRKY11 cooperates with CsNPR1 to regulate SA-triggered leaf de-greening and reactive oxygen species burst in cucumber.Molecular horticulture · 2024Article
- Comparative Transcriptome Analysis between Resistant and Susceptible Pakchoi Cultivars in Response to Downy Mildew.International journal of molecular sciences · 2023Article
- WHIRLY protein functions in plants.Food and energy security · 2023Review
- Morphological and Genetic Diversity of Cucumber (Plants (Basel, Switzerland) · 2022Review
- The CsHEC1-CsOVATE module contributes to fruit neck length variation via modulating auxin biosynthesis in cucumber.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Research Progress on the Leaf Morphology, Fruit Development and Plant Architecture of the Cucumber.Plants (Basel, Switzerland) · 2022Review
- Population-specific, recent positive selection signatures in cultivated Cucumis sativus L. (cucumber).G3 (Bethesda, Md.) · 2022Article
- SPATULA and ALCATRAZ confer female sterility and fruit cavity via mediating pistil development in cucumber.Plant physiology · 2022Article
- Genome-Wide Identification ofGenes · 2022Article
- Research Advances in Genetic Mechanisms of Major Cucumber Diseases Resistance.Frontiers in plant science · 2022Review
- Engineering Macromolecular Trafficking Into the Citrus Vasculature.Frontiers in plant science · 2022Article
- Garlic Volatile Diallyl Disulfide Induced Cucumber Resistance to Downy Mildew.International journal of molecular sciences · 2021Article
- HECATE2 acts with GLABROUS3 and Tu to boost cytokinin biosynthesis and regulate cucumber fruit wart formation.Plant physiology · 2021Article
- Two MADS-box genes regulate vascular cambium activity and secondary growth by modulating auxin homeostasis inPlant communications · 2021Article
- Genetic regulation of shoot architecture in cucumber.Horticulture research · 2021Review
- The mechanism of sesame resistance against Macrophomina phaseolina was revealed via a comparison of transcriptomes of resistant and susceptible sesame genotypes.BMC plant biology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Domesticated crops with high yield and quality are frequently susceptible to pathogen attack, whereas enhancement of disease resistance generally compromises crop yield. The underlying mechanisms of how plant development and disease resistance are coordinately programed remain elusive. Here, we showed that the basic Helix-Loop-Helix (bHLH) transcription factor Cucumis sativus Irregular Vasculature Patterning (CsIVP) was highly expressed in cucumber vascular tissues. Knockdown of CsIVP caused severe vasculature disorganization and abnormal organ morphogenesis. CsIVP directly binds to vascular-related regulators YABBY5 (CsYAB5), BREVIPEDICELLUS (CsBP), and AUXIN/INDOLEACETIC ACIDS4 (CsAUX4) and promotes their expression. Knockdown of CsYAB5 resulted in similar phenotypes as CsIVP-RNA interference (RNAi) plants, including disturbed vascular configuration and abnormal organ morphology. Meanwhile, CsIVP-RNAi plants were more resistant to downy mildew and accumulated more salicylic acid (SA). CsIVP physically interacts with NIM1-INTERACTING1 (CsNIMIN1), a negative regulator in the SA signaling pathway. Thus, CsIVP is a novel vasculature regulator functioning in CsYAB5-mediated organ morphogenesis and SA-mediated downy mildew resistance in cucumber.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.