Evidence map›Paper›PMID 32203448›Full record

ReviewHypertension research : official journal of the Japanese Society of Hypertension2020

Blood pressure variability: its relevance for cardiovascular homeostasis and cardiovascular diseases.

Gianfranco Parati, Camilla Torlasco, Martino Pengo, Grzegorz Bilo, Juan Eugenio Ochoa

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Hypertension research : official journal of the Japanese Society of Hypertension, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06394934 (Impact of Home and Clinical Blood Pressure Variability on Arteriosclerosis and Metabolic Indicators), which is not on this map. Cited by 83 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06394934 recruitingnot on this mapstarted 2024, after this paper: background citation

Impact of Home and Clinical Blood Pressure Variability on Arteriosclerosis and Metabolic Indicators

Typeobservational_patient_registrySponsorKorea University Anam HospitalRan2024 to 2029Enrolled4,188ConditionsHypertension, Blood Pressure Monitoring, Home, Arteriosclerosis, Metabolic Syndrome XArmsHealthscan App
3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  12. Elevated blood pressure variability links cardiac autonomic dysfunction to complex arrhythmias in hypertension.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026
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23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gianfranco ParatiDepartment of Cardiovascular Neural and Metabolic Sciences, Istituto Auxologico Italiano, IRCCS, S.Luca Hospital, Milan, Italy. gianfranco.parati@unimib.it.
Camilla TorlascoDepartment of Cardiovascular Neural and Metabolic Sciences, Istituto Auxologico Italiano, IRCCS, S.Luca Hospital, Milan, Italy.
Martino PengoDepartment of Cardiovascular Neural and Metabolic Sciences, Istituto Auxologico Italiano, IRCCS, S.Luca Hospital, Milan, Italy.
Grzegorz BiloDepartment of Cardiovascular Neural and Metabolic Sciences, Istituto Auxologico Italiano, IRCCS, S.Luca Hospital, Milan, Italy.
Juan Eugenio OchoaDepartment of Cardiovascular Neural and Metabolic Sciences, Istituto Auxologico Italiano, IRCCS, S.Luca Hospital, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blood pressure (BP) is one of the most dynamic physiologic variables that is routinely measured in clinical practice and is characterized by continuous and significant changes beat-to-beat, over 24 h, day-to-day, and visit-to-visit. Under physiological conditions, these BP variations largely represent a response to environmental stimulations and challenges of daily life aimed at maintaining so-called cardiovascular "homeostasis". However, sustained increases in blood pressure variability (BPV) may also reflect alterations in cardiovascular regulatory mechanisms or underlying pathological conditions and may represent a source of damage to the cardiovascular system. The clinical significance and prognostic implications of these BP variations have been demonstrated by a series of clinical and population studies conducted in recent years, in which increasing BPV has been associated with a higher risk of subclinical organ damage, cardiovascular events, and cardiovascular and all-cause mortality, independent of elevated average BP values. This paper will review the available evidence on the current definitions, classification, and mechanisms responsible for different types of BPV by focusing on their relevance to cardiovascular homeostasis and cardiovascular disease.

Indexed as

Blood PressureCardiovascular DiseasesCardiovascular SystemHomeostasisHumansPrognosisBlood pressure variabilityCardiovascular regulatory mechanismsCardiovascular risk.Subclinical organ damage

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.