ArticleHeredity2020
Chromosomal assembly and analyses of genome-wide recombination rates in the forest pathogenic fungus Armillaria ostoyae.
Article in Heredity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 30 citations in OpenAlex.
- Genetic variation among progeny shapes symbiosis in a basidiomycete with poplar.The New phytologist · 2025Article
- High-Quality Draft Genome for Armillaria mexicana, a Recently Described Species in North America.Genome biology and evolution · 2025Article
- Morphogenesis, starvation, and light responses in a mushroom-forming fungus revealed by long-read sequencing and extensive expression profiling.Cell genomics · 2025Article
- Patterns and mechanisms of fungal genome plasticity.Current biology : CB · 2025Review
- A systematic screen for co-option of transposable elements across the fungal kingdom.Mobile DNA · 2024Article
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- Genomic and Transcriptomic Approaches Provide a Predictive Framework for Sesquiterpenes Biosynthesis inJournal of fungi (Basel, Switzerland) · 2023Article
- A genetic linkage map and improved genome assembly of the termite symbiont Termitomyces cryptogamus.BMC genomics · 2023Article
- Article
- Transgenerational genomic analyses reveal allelic oscillation and purifying selection in a gut parasiteFrontiers in microbiology · 2022Article
- On how to generalize species-specific conceptual schemes to generate a species-independent Conceptual Schema of the Genome.BMC bioinformatics · 2021Article
- Macrosynteny analysis between Lentinula edodes and Lentinula novae-zelandiae reveals signals of domestication in Lentinula edodes.Scientific reports · 2021Article
- Epidemiology, Biotic Interactions and Biological Control of Armillarioids in the Northern Hemisphere.Pathogens (Basel, Switzerland) · 2021Review
- Article
Corrections and comments
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Authors and funding
5 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recombination shapes the evolutionary trajectory of populations and plays an important role in the faithful transmission of chromosomes during meiosis. Levels of sexual reproduction and recombination are important properties of host-pathogen interactions because the speed of antagonistic co-evolution depends on the ability of hosts and pathogens to generate genetic variation. However, our understanding of the importance of recombination is limited because large taxonomic groups remain poorly investigated. Here, we analyze recombination rate variation in the basidiomycete fungus Armillaria ostoyae, which is an aggressive pathogen on a broad range of conifers and other trees. We analyzed a previously constructed, dense genetic map based on 198 single basidiospore progeny from a cross. Progeny were genotyped at a genome-wide set of single-nucleotide polymorphism (SNP) markers using double digest restriction site associated DNA sequencing. Based on a linkage map of on 11,700 SNPs spanning 1007.5 cM, we assembled genomic scaffolds into 11 putative chromosomes of a total genome size of 56.6 Mb. We identified 1984 crossover events among all progeny and found that recombination rates were highly variable along chromosomes. Recombination hotspots tended to be in regions close to the telomeres and were more gene-poor than the genomic background. Genes in proximity to recombination hotspots were encoding on average shorter proteins and were enriched for pectin degrading enzymes. Our analyses enable more powerful population and genome-scale studies of a major tree pathogen.
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