Evidence map›Paper›PMID 32203230›Full record

SynthesisEuropean journal of clinical nutrition2020

Effects of nutritional support on the clinical outcomes of well-nourished patients with cancer: a meta-analysis.

Xingxia Zhang, Xinrong Chen, Jie Yang, Yanjie Hu, Ka Li

Abstract readMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in European journal of clinical nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xingxia ZhangWest China School of Nursing, Sichuan University, Chengdu, 610041, China.ORCID http://orcid.org/0000-0001-9934-6834
Xinrong ChenWest China School of Nursing, Sichuan University, Chengdu, 610041, China.
Jie YangDepartment of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu, 610041, China.
Yanjie HuWest China School of Nursing, Sichuan University, Chengdu, 610041, China.
Ka LiWest China School of Nursing, Sichuan University, Chengdu, 610041, China. lika127@126.com.
Sichuan University · CN

Funding

National Natural Science Foundation of China (National Science Foundation of China) 71974135
6 · The paper itself

Abstract

The effects of nutritional support on well-nourished patients have been investigated, but the results were inconsistent among different articles. We performed the meta-analysis to examine the existing evidence. We systematically retrieved articles from PubMed, Web of Science and the Cochrane Library to identify the evidence of nutritional support for well-nourished patients. Methodological quality assessment was assessed based on the Cochrane Handbook and GRADE. Nine randomized controlled trials (RCTs) and one non-RCT with 1400 participants were included in this meta-analysis. Nutritional support, particularly immunonutrition, was associated with a significant reduction in postoperative infectious complications (OR = 0.74, 95% CI: 0.57-0.96), and a decreasing trends in morbidity and the length of the hospital stay (LOS) were observed. However, the mortality rates were comparable between two groups. The quality of evidence was moderate to high. Nutritional support, particularly immunonutrition supplementation, is likely to reduce infectious complications, morbidity and LOS without influencing mortality and may be a safe and preferred choice for well-nourished patients undergoing surgery for cancer. However, additional RCTs are warranted to determine the effects of nutritional support on well-nourished patients.

Indexed as

NeoplasmsNutritional SupportHumansLength of StayPostoperative ComplicationsRandomized Controlled Trials as Topic

Identifiers

PMID32203230
OpenAlexW3011222921

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.