Evidence map›Paper›PMID 32203211›Full record

ArticleBritish journal of cancer2020

Female reproductive factors and the risk of lung cancer in postmenopausal women: a nationwide cohort study.

Keun Hye Jeon, Dong Wook Shin, Kyungdo Han, Dahye Kim, Jung Eun Yoo, Su-Min Jeong, Jong Ho Cho

Open access · hybridAbstract read
In one paragraph

Article in British journal of cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Review
  3. Sex, hormones, and lung health.Physiological reviews · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Sex-specificity in Surgical Stages of Lung Cancer in Young Adults.The open respiratory medicine journal · 2023
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Role of sex hormones in lung cancer.Experimental biology and medicine (Maywood, N.J.) · 2021
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Keun Hye JeonDepartment of Family Medicine and Supportive Care Centre, Samsung Medical Centre, Sungkyunkwan University School of Medicine, Seoul, Korea.
Dong Wook ShinDepartment of Family Medicine and Supportive Care Centre, Samsung Medical Centre, Sungkyunkwan University School of Medicine, Seoul, Korea. dwshin.md@gmail.com.ORCID http://orcid.org/0000-0001-8128-8920
Kyungdo HanDepartment of Medical Statistics, The Catholic University of Korea, Seoul, Korea. hkd917@naver.com.
Dahye KimDepartment of Medical Statistics, The Catholic University of Korea, Seoul, Korea.
Jung Eun YooDepartment of Family Medicine and Supportive Care Centre, Samsung Medical Centre, Sungkyunkwan University School of Medicine, Seoul, Korea.
Su-Min JeongDepartment of Family Medicine and Supportive Care Centre, Samsung Medical Centre, Sungkyunkwan University School of Medicine, Seoul, Korea.
Jong Ho ChoDepartment of Thoracic Surgery, Samsung Medical Centre, Sungkyunkwan University School of Medicine, Seoul, Korea.
Samsung Medical Center · KRCatholic University of Korea · KRHarvard University · USRAND Corporation · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundReproductive factors and hormone use in postmenopausal women have been hypothesised to affect the risk of developing lung cancer, but the epidemiological evidence is inconsistent.

methodsUsing the Korean National Health Insurance System database, we identified 4,775,398 postmenopausal women older than 40 years who had undergone both cardiovascular health- and cancer screening between 1 January 2009 and 31 December 2014. Information about reproductive factors was obtained from a self-administered questionnaire. The risk of lung cancer was estimated using Cox proportional hazard regression models.

resultsDuring a median follow-up of 4.4 years, 16,556 women (15,223 non-smokers) were diagnosed with lung cancer. The risk of lung cancer was not significantly influenced by early menarche age (adjusted hazard ratio [aHR] 1.03 for menarche ≥18 vs. ≤14; 95% confidence interval [CI], 0.98-1.09) or late age at menopause (aHR 1.02 for menopause ≥55 vs. <40; 95% CI, 0.91-1.14). Furthermore, the number of children, duration of breastfeeding and use of hormone replacement therapy were not associated with the risk of lung cancer.

conclusionsNo statistically significant association was found between reproductive factors and the risk of lung cancer in postmenopausal Korean women.

Indexed as

AdultAgedBreast FeedingEarly Detection of CancerEstrogen Replacement TherapyFemaleGenetic FitnessGenitalia, FemaleHumansLung NeoplasmsMenopauseMiddle AgedPostmenopauseProportional Hazards ModelsReproductive HistoryRisk Factors

Identifiers

PMID32203211
PMCPMC7188895
OpenAlexW3011607625

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.