Evidence map›Paper›PMID 32203188›Full record

ArticleCellular & molecular immunology2020

Functional exhaustion of antiviral lymphocytes in COVID-19 patients.

Meijuan Zheng, Yong Gao, Gang Wang, Guobin Song, Siyu Liu, Dandan Sun, Yuanhong Xu, Zhigang Tian

3 registry-linked trialsAbstract readLetterComment
In one paragraph

Article in Cellular & molecular immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 1,116 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,116citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04596098 completednot on this map

Immune Responses to COVID-19 (SARS-CoV-2 Related Infection); Isolation of Human Neutralizing Monoclonal Antibodies for Therapeutics and Vaccine Design Approaches: a Prospective Monocentric Trial With Collaborative Sample Collection.

TypeobservationalSponsorUniversity Hospital, GrenobleRan2020 to 2022Enrolled55ConditionsSARS-CoV 2ArmsBlood sampling
NCT04816760 unknown statusnot on this map

Alterations of Innate and Adaptive Immune Cells During the Course of SARS CoV-2 Pneumonia

TypeobservationalSponsorInstitut Hospitalo-Universitaire Méditerranée InfectionRan2020 to 2021Enrolled100ConditionsSars-CoV2, Innate Immunity, Immunization, InfectionArmsPeripheral blood samples
NCT04880720 completednot on this mapstarted 2021, after this paper: background citation

Deciphering a Specific Signature of the Immunosenescence Induced in COVID-19+ Patients Versus Rheumatoid Arthritis Patients

TypeobservationalSponsorUniversity Hospital, MontpellierRan2021 to 2022Enrolled43ConditionsSARS-Cov-2 Infection, Rheumatoid ArthritisArmsBlood sampling
3 · Its place in the literature

Who cites it

1,116 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Systematic review with meta-analysis of active herpesvirus infections in patients with COVID-19: Old players on the new field.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2023
    Pooled it
  4. Gut distress and interventionFrontiers in public health · 2023
    Pooled it
  5. Trial
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  16. Single-cell Tree-based Model for Genomic-Disease Association.bioRxiv : the preprint server for biology · 2026
    Article
  17. Review
  18. Article
  19. Review
  20. Article

1,056 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Meijuan ZhengDepartment of Clinical Laboratory, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China. mjzheng@mail.ustc.edu.cn.
Yong GaoDepartment of Clinical Laboratory, Fuyang Second People's Hospital, Fuyang Infectious Disease Clinical College, Anhui Medical University, Fuyang, Anhui, China.
Gang WangDepartment of Clinical Laboratory, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Guobin SongDepartment of Clinical Laboratory, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Siyu LiuDepartment of Clinical Laboratory, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Dandan SunDepartment of Clinical Laboratory, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Yuanhong XuDepartment of Clinical Laboratory, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China. xyhong1964@163.com.
Zhigang TianDivision of Molecular Medicine, Hefei National Laboratory for Physical Sciences at Microscale, the CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, China. tzg@ustc.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antiviral AgentsHepatitis CBetacoronavirusCoronavirus InfectionsCOVID-19HumansKiller Cells, NaturalPandemicsPneumonia, ViralSARS-CoV-2Antiviral Agents

Identifiers

PMID32203188
PMCPMC7091858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.