Evidence map›Paper›PMID 32202920›Full record

Trial reportAIDS education and prevention : official publication of the International Society for AIDS Education2020

Acceptability, Feasibility, and Preliminary Efficacy of a Resilience-Oriented Family Intervention to Prevent Adolescent HIV and Depression: A Pilot Randomized Controlled Trial.

Caroline Kuo, Catherine Mathews, Danielle Giovenco, Millicent Atujuna, William Beardslee, Jacqueline Hoare, Dan J Stein, Larry K Brown

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in AIDS education and prevention : official publication of the International Society for AIDS Education, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02432352 (Our Family Our Future), which is not on this map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02432352 phase1completednot on this map

Our Family Our Future: Family Prevention of HIV Risk and Depression in HIV-endemic South Africa

TypeinterventionalSponsorBrown UniversityRan2015 to 2017Enrolled146ConditionsSexual Behavior, DepressionArmsOur Family Our Future
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

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  16. Implementing Task-Shared Child and Adolescent Psychological Interventions in Low- and Middle-Income Countries: A Scoping Review.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Caroline KuoBrown University School of Public Health, Providence, Rhode Island.
Catherine MathewsHealth Systems Research Unit, South African Medical Research Council, Tygerberg, South Africa.
Danielle GiovencoUniversity of North Carolina at Chapel Hill, Gillings School of Global Public Health.
Millicent AtujunaDesmond Tutu HIV Foundation, Cape Town, South Africa.
William BeardsleeJudge Baker Children's Center, Harvard Medical School, and Boston Children's Hospital, Boston, Massachusetts.
Jacqueline HoareUniversity of Cape Town.
Dan J SteinSouth African Medical Research Council Unit on Risk & Resilience in Mental Disorders, University of Cape Town.
Larry K BrownAlpert Medical School of Brown University, Providence, Rhode Island, and the Providence/Boston Center for AIDS Research.
Brown University · USDesmond Tutu HIV Foundation · ZASouth African Medical Research Council · ZAUniversity of Cape Town · ZAUniversity of North Carolina at Chapel Hill · US

Funding

Family Prevention of HIV Risk and Depression in HIV-endemic South AfricaK01MH096646 · NIMH · BROWN UNIVERSITY · PI KUO, CAROLINE CHIA · 2012 to 2016
$871k
NIMH NIH HHS K01 MH096646NIMH NIH HHS L30 MH098313
6 · The paper itself

Abstract

We tested the acceptability, feasibility, and preliminary efficacy of Our Family Our Future, a resilience-oriented intervention engaging families in prevention of adolescent HIV and depression. South African adolescents, 13-15 years of age, with mild depressive symptoms, were randomized to intervention or wait-list using parallel assignment in a single-blind trial. HIV risk behavior and depression were evaluated at baseline, 1, and 3 months. We examined intervention satisfaction, fidelity, trial retention, and preliminary efficacy. One hundred-ninety-six adolescent-parent dyads completed eligibility screening and baseline, and n = 73 dyads were randomized. All families ranked intervention quality as good or excellent. Over 90% were satisfied with content. Facilitators were adherent to intervention protocol. All families were retained in post-intervention assessments. Intervention recipients reported diminished depressive symptoms, inconsistent condom use, and sexual activity, as well as increased HIV testing. Our Family Our Future is highly acceptable and feasible and should be tested in a future efficacy trial.

Indexed as

Patient Acceptance of Health CareResilience, PsychologicalAdolescentAdolescent BehaviorDepressionFeasibility StudiesFemaleHIV InfectionsHumansMaleMass ScreeningParentsPilot ProjectsSafe SexSexual BehaviorSingle-Blind Methoddepressionfamily interventionpreventionresilienceSouth Africa

Identifiers

PMID32202920
PMCPMC7250140
OpenAlexW3012864276

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.