Evidence map›Paper›PMID 32202792›Full record

ArticleMolecular pharmaceutics2020

Carolina A Ferreira, Emily B Ehlerding, Zachary T Rosenkrans, Dawei Jiang, Tuanwei Sun, Eduardo Aluicio-Sarduy, Jonathan W Engle, Dalong Ni, Weibo Cai

Open access · greenAbstract read
In one paragraph

Article in Molecular pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Protein-functionalized and intrinsically radiolabeled [European journal of nuclear medicine and molecular imaging · 2025
    Article
  3. Siderocalin fusion proteins enable a newRSC chemical biology · 2023
    Article
  4. Article
  5. Advances and Prospects in the Treatment of Pancreatic Cancer.International journal of nanomedicine · 2023
    Review
  6. Article
  7. Production Review of Accelerator-Based Medical Isotopes.Molecules (Basel, Switzerland) · 2022
    Review
  8. Article
  9. TheragnosticFrontiers in medicine · 2022
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Tissue Factor-Targeted ImmunoPET Imaging and Radioimmunotherapy of Anaplastic Thyroid Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Carolina A FerreiraDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.
Emily B EhlerdingDepartment of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.
Zachary T RosenkransDepartment of Pharmaceutical Sciences, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.
Dawei JiangDepartment of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.ORCID 0000-0002-4072-0075
Tuanwei SunDepartment of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.
Eduardo Aluicio-SarduyDepartment of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.
Jonathan W EngleDepartment of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.
Dalong NiDepartment of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.ORCID 0000-0001-6679-5414
Weibo CaiDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.ORCID 0000-0003-4641-0833
University of Wisconsin–Madison · US

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Christian Capitini · 1985 to 2026
$142.6M
U.W. RADIOLOGICAL SCIENCES TRAINING PROGRAMT32CA009206 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Bryan Patrick Bednarz · 1985 to 2026
$12.1M
NCI NIH HHS P30 CA014520NCI NIH HHS T32 CA009206
6 · The paper itself

Abstract

Pancreatic cancer is highly aggressive, with a median survival time of less than 6 months and a 5-year overall survival rate of around 7%. The poor prognosis of PaCa is largely due to its advanced stage at diagnosis and the lack of efficient therapeutic options. Thus, the development of an efficient, multifunctional PaCa theranostic system is urgently needed. Overexpression of tissue factor (TF) has been associated with increased tumor growth, angiogenesis, and metastasis in many malignancies, including pancreatic cancer. Herein, we propose the use of a TF-targeted monoclonal antibody (ALT836) conjugated with the pair

Indexed as

AnimalsAntibodies, MonoclonalCell Line, TumorFemaleMicePancreatic NeoplasmsPositron-Emission TomographyThromboplastinTissue DistributionYttrium RadioisotopesAntibodies, MonoclonalThromboplastinYttrium Radioisotopespancreatic cancerpositron emission tomography (PET)radioimmunotherapytheranosticstissue factoryttrium-86yttrium-90

Identifiers

PMID32202792
PMCPMC7265990
OpenAlexW3012784466

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.