Evidence map›Paper›PMID 32202699›Full record

ArticleCancer medicine2020

Prediagnostic adult body mass index change and esophageal adenocarcinoma survival.

Elizabeth A Loehrer, Edward L Giovannucci, Rebecca A Betensky, Andrea Shafer, David C Christiani

Abstract read
In one paragraph

Article in Cancer medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elizabeth A LoehrerDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0003-1249-4442
Edward L GiovannucciDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Rebecca A BetenskyDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Andrea ShaferDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
David C ChristianiDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Funding

The HSPH Education and Research Center of Occupational Safety and HealthT42OH008416 · OH · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI CHRISTIANI, DAVID C · 2005 to 2025
$30.5M
NIOSH CDC HHS T42 OH008416
6 · The paper itself

Abstract

backgroundWe examined whether body mass index (BMI) changes in adulthood, prior to disease onset, are associated with overall survival among esophageal adenocarcinoma patients.

methodsWe included 285 histologically confirmed patients with a complete baseline BMI questionnaire. Using extended Cox regression models, we obtained adjusted hazard ratios (HRs) for the associations between overall survival and BMI at diagnosis, BMI 6 months before diagnosis, self-reported average adult BMI, and ΔBMI (BMI 6 months before diagnosis minus average adult BMI), categorized into tertiles <0 kg/m

resultsBody mass index at diagnosis >25 and <35 kg/m

conclusionBody mass index gain in adulthood is associated with poor overall survival, and maintaining a normal body weight throughout adulthood is associated with the best overall survival among esophageal adenocarcinoma patients, independent of BMI at diagnosis.

Indexed as

Body Mass IndexBody-Weight TrajectoryAdenocarcinomaAgedEsophageal NeoplasmsFemaleHumansMaleMiddle AgedObesityOverweightPrognosisProportional Hazards ModelsRisk FactorsSurvival Rateadenocarcinomabody mass indexbody weight changesesophageal neoplasmssurvival analysis

Identifiers

PMID32202699
PMCPMC7221446

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.