Evidence map›Paper›PMID 32202492›Full record

ArticleeLife2020

Long non-coding RNA

Nguyen Pt Huynh, Catherine C Gloss, Jeremiah Lorentz, Ruhang Tang, Jonathan M Brunger, Audrey McAlinden, Bo Zhang, Farshid Guilak

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. LncRNANon-coding RNA research · 2025
    Article
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  7. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Nguyen Pt HuynhDepartment of Orthopaedic Surgery, Washington University, St Louis, United States.ORCID 0000-0002-7254-1645
Catherine C GlossDepartment of Orthopaedic Surgery, Washington University, St Louis, United States.
Jeremiah LorentzDepartment of Orthopaedic Surgery, Washington University, St Louis, United States.
Ruhang TangDepartment of Orthopaedic Surgery, Washington University, St Louis, United States.
Jonathan M BrungerDepartment of Biomedical Engineering, Vanderbilt University, Nashville, United States.
Audrey McAlindenDepartment of Orthopaedic Surgery, Washington University, St Louis, United States.
Bo ZhangCenter of Regenerative Medicine, Washington University, St Louis, United States.
Farshid GuilakDepartment of Orthopaedic Surgery, Washington University, St Louis, United States.ORCID 0000-0001-7380-0330
Washington University in St. Louis · USDuke University · USVanderbilt University · US

Funding

Thermally-Triggered Intra-articular Drug Delivery for OAP01AR050245 · NIAMS · DUKE UNIVERSITY · PI GUILAK, FARSHID · 2003 to 2012
$11.5M
VISCOELASTIC PROPERTIES OF NORMAL AND OA CHONDRONSR01AG015768 · NIA · WASHINGTON UNIVERSITY · PI GUILAK, FARSHID · 1998 to 2022
$7.7M
Washington University Rheumatic DiseasesResearch Resource-based CenterP30AR073752 · NIAMS · WASHINGTON UNIVERSITY · PI Christine T. Pham · 2018 to 2026
$7.6M
Resource Based Center for Musculoskeletal Biology and Medicine (Overall Application)P30AR074992 · NIAMS · WASHINGTON UNIVERSITY · PI MATTHEW J SILVA · 2019 to 2026
$6.8M
Epigenetic Regulation in Cartilage TissueR01AR069605 · NIAMS · WASHINGTON UNIVERSITY · PI Regis J O'Keefe · 2016 to 2026
$3.5M
OBESITY, BIOMECHANICS, AND INFLAMMATION IN OSTEOARTHRITISR01AG046927 · NIA · WASHINGTON UNIVERSITY · PI GUILAK, FARSHID · 2013 to 2023
$3.2M
MicroRNA regulation of bone formation and repairR01AR075730 · NIAMS · WASHINGTON UNIVERSITY · PI MCALINDEN, AUDREY · 2020 to 2024
$2.4M
Regulation of Skeletal Development by microRNAsR01AR064191 · NIAMS · WASHINGTON UNIVERSITY · PI MCALINDEN, AUDREY · 2014 to 2018
$1.7M
Regulation of Chondrogenesis by Long Non-Coding RNAsR21AR072193 · NIAMS · WASHINGTON UNIVERSITY · PI MCALINDEN, AUDREY · 2018 to 2019
$369k
NIAMS NIH HHS P01 AR050245NIAMS NIH HHS P30 AR073752NIAMS NIH HHS P30 AR074992NIAMS NIH HHS R01 AR064191NIAMS NIH HHS R01 AR069605NIAMS NIH HHS R01 AR075730NIAMS NIH HHS R21 AR072193NIA NIH HHS R01 AG015768NIA NIH HHS R01 AG046927
6 · The paper itself

Abstract

The roles of long noncoding RNAs (lncRNAs) in musculoskeletal development, disease, and regeneration remain poorly understood. Here, we identified the novel lncRNA

Indexed as

Gene Expression Regulation, DevelopmentalSignal TransductionBinding SitesCell DifferentiationCells, CulturedChondrocytesChondrogenesisExtracellular MatrixGene EditingGene Expression ProfilingGene Regulatory NetworksHumansImmunohistochemistryInterferon-gammaMesenchymal Stem CellsProtein BindingInterferon-gammaRNA, Long Noncodinghumanmesenchymal stem cellsregenerative medicineRNF144A-AS1stem cellstissue engineering

Identifiers

PMID32202492
PMCPMC7202894
OpenAlexW3012586848

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.