Evidence map›Paper›PMID 32202416›Full record

ArticleBiochemistry2020

A Modular RNA Domain That Confers Differential Ligand Specificity.

Andrew J Knappenberger, Caroline W Reiss, Caroline M Focht, Scott A Strobel

Open access · greenAbstract read
In one paragraph

Article in Biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Variants of the guanine riboswitch class exhibit altered ligand specificities for xanthine, guanine, or 2'-deoxyguanosine.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  3. Article
  4. An uncommon [KRNA (New York, N.Y.) · 2021
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Andrew J KnappenbergerDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06510, United States.
Caroline W ReissDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06510, United States.
Caroline M FochtDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06510, United States.
Scott A StrobelDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06510, United States.ORCID 0000-0001-8402-4226
Yale University · US

Funding

X-RAY ANALYSIS OF PROTEIN STRUCTURE AND FUNCTIONP01GM022778 · NIGMS · YALE UNIVERSITY · PI BREAKER, RONALD R · 1985 to 2019
$26.1M
Training Program in Molecular MedicineT32GM100884 · NIGMS · YALE UNIVERSITY · PI LISTER, GEORGE, NITABACH, MICHAEL · 2013 to 2022
$1.8M
NIGMS NIH HHS P01 GM022778NIGMS NIH HHS T32 GM100884
6 · The paper itself

Abstract

The modularity of protein domains is well-known, but the existence of independent domains that confer function in RNA is less established. Recently, a family of RNA aptamers termed

Indexed as

Aptamers, NucleotideGuanosine TetraphosphateLigandsModels, MolecularNucleic Acid ConformationPhosphoribosyl PyrophosphateAptamers, NucleotideGuanosine TetraphosphateLigandsPhosphoribosyl Pyrophosphate

Identifiers

PMID32202416
PMCPMC7311191
OpenAlexW3012625045

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.