ArticleScandinavian journal of work, environment & health2020
Persistent and changing job strain and risk of coronary heart disease. A population-based cohort study of 1.6 million employees in Denmark.
Article in Scandinavian journal of work, environment & health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- The demands-control-support work stress model and risk of ischemic heart disease: causal inference based on observational epidemiology.Scandinavian journal of work, environment & health · 2026Pooled it
- Work Exposures and Development of Cardiovascular Diseases: A Systematic Review.Annals of work exposures and health · 2022Pooled it
- Occupational differences in working life expectancy and working years lost in Nordic countries.Scandinavian journal of work, environment & health · 2025Article
- Occupational exposures and coronary heart disease in the Hamburg City Health Study (HCHS) - a cross-sectional study.BMC public health · 2025Article
- Healthy enough to work up to age 67 and beyond? A longitudinal population-based study on time trends in working life expectancy free of cardiovascular diseases based on German health insurance data.BMJ public health · 2024Article
- Influence of Socioeconomic Status on the Presence of Obstructive Coronary Artery Disease and Cardiovascular Outcomes in Patients Undergoing Invasive Coronary Angiography.Healthcare (Basel, Switzerland) · 2024Article
- Increased job strain and cardiovascular disease mortality: a prospective cohort study in U.S. workers.Industrial health · 2023Article
- Ways to study changes in psychosocial work factors.Scandinavian journal of work, environment & health · 2023Article
- Workplace psychosocial resources and risk of cardiovascular disease among employees: a multi-cohort study of 135 669 participants.Scandinavian journal of work, environment & health · 2022Article
- Combined psychosocial work factors and risk of long-term sickness absence in the general working population: Prospective cohort with register follow-up among 69 371 workers.Scandinavian journal of work, environment & health · 2022Article
- Emotional demands at work and risk of hospital-treated depressive disorder in up to 1.6 million Danish employees: a prospective nationwide register-based cohort study.Scandinavian journal of work, environment & health · 2022Article
- Work stress and loss of years lived without chronic disease: an 18-year follow-up of 1.5 million employees in Denmark.European journal of epidemiology · 2022Article
- A cross-sectional study to assess job strain of emergency healthcare workers by Karasek questionnaire: The SEEK study.Frontiers in psychiatry · 2022Article
- Psychosocial work factors and blood pressure among 63 800 employees from The Netherlands in the Lifelines Cohort Study.Journal of epidemiology and community health · 2022Article
- Understanding the impact of psychosocial working conditions on workers' health: we have come a long way, but are we there yet?Scandinavian journal of work, environment & health · 2021Article
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Authors and funding
12 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives This study aimed to examine the association between job strain and incident coronary heart disease (CHD) in Denmark, while accounting for changes of job strain. Methods We included all employees residing in Denmark in 2000, aged 30-59 years with no prevalent CHD (N=1 660 150). We determined exposure to job strain from 1996-2009 using a job exposure matrix (JEM) with annual updates. Follow-up for incident CHD was from 2001-2010 via linkage to health records. We used Cox regression to calculate hazard ratios (HR) and 95% confidence intervals (CI) for the association between job strain and incident CHD. Results During 16.1 million person-years, we identified 24 159 incident CHD cases (15.0 per 10 000 person-years). After adjustment for covariates, job strain in 2000 predicted onset of CHD during a mean follow-up of 9.71 years (HR 1.10, 95% CI 1.07-1.13). When analyzing changes in job strain from one year to the next and CHD in the subsequent year, persistent job strain (HR 1.07, 95% CI 1.03-1.10), onset of job strain (HR 1.20, 95% CI 1.12-1.29) and removal of strain (HR 1.20, 95% CI 1.12-1.28) were associated with higher CHD incidence compared to persistent no job strain. Associations were similar among men and women. Conclusions Job strain is associated with a higher risk of incident CHD in Denmark. As we used a JEM, we can rule out reporting bias. However, under- or overestimation of associations is possible due to non-differential misclassification of job strain and residual confounding by socioeconomic position.
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