ArticleOrthopaedic surgery2020
Relationship Between Time to Surgical Debridement and the Incidence of Infection in Patients with Open Tibial Fractures.
Article in Orthopaedic surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Comparing external fixators and intramedullary nailing for treating open tibia fractures: a meta-analysis of randomized controlled trials.Journal of orthopaedic surgery and research · 2023Pooled it
- In Vitro Antibacterial Efficacy of a New TiONanomaterials (Basel, Switzerland) · 2025Article
- Complications and Functional Outcomes in Open Tibia-Fibula Fractures: A Retrospective Analysis from a Tertiary Care Centre.Journal of orthopaedic case reports · 2025Article
- Analysis of risk factors, pathogenic bacteria characteristics, and drug resistance of postoperative surgical site infection in adults with limb fractures.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2025Article
- A Linked Population-Based Analysis of Severe Lower Extremity Traumas in Ontario.Plastic surgery (Oakville, Ont.) · 2025Article
- Open Tibial Fractures Part 1: A Narrative Review of Initial Treatment and Potential Applicability to the Southern African Context.Orthopedic research and reviews · 2025Review
- Risk of infection and conversion time from external to definitive fixation in open tibial fracture.Journal of orthopaedic surgery and research · 2024Article
- A Novel Uni- and Biplanar External Fixator for Initial and Definitive Complex Foot Trauma.Foot & ankle orthopaedics · 2024Article
- Distribution of pathogens and risk factors for post-replantation wound infection in patients with traumatic major limb mutilation.PloS one · 2024Article
- Article
- Bacterial Epidemiology of Surgical Site Infections after Open Fractures of the Lower Limb: A Retrospective Cohort Study.Antibiotics (Basel, Switzerland) · 2021Article
- Study on the relationship between the timing of conversion from external fixation to internal fixation and infection in the treatment of open fractures of extremities.Journal of orthopaedic surgery and research · 2021Article
- Fracture, nonunion and postoperative infection risk in the smoking orthopaedic patient: a systematic review and meta-analysis.EFORT open reviews · 2021Review
- The Effect of Delayed Surgical Debridement in the Management of Open Tibial Fractures: A Systematic Review and Meta-Analysis.Diagnostics (Basel, Switzerland) · 2021Review
- Article
- Short term results with the use of PLA antibiotic coated nail in open tibia fractures: A prospective study.Journal of orthopaedicsArticle
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7 authors at 1 institution in 1 country.
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Abstract
objectiveTo analyze the relationship between the length from injury to first debridement (LFITFD) of open tibial fractures and perioperative infection, and explore independent risk factors related to infection.
methodsThis retrospective study focused on 215 clinical patients with open tibial fractures who were admitted from January 2012 to January 2017. According to the time from injury to the operation, the patients were categorized into four groups: LFITFD ≤ 6 h, 6 < LFITFD ≤ 12 h, 12 < LFITFD≤24 h, and (LFITFD > 24 h). Infection risk factors were screened by univariate analysis, and multivariate logistic regression analysis was used to determine independent risk factors.
resultsThe infection rates of four groups were 9.2%, 9.5%, 11.1%, and 10.5% with six of 65, nine of 95, four of 36, and two of 19 patients being infected, respectively. There was no statistical significance between the four groups. The infection rates among fractures of different Gustilo-Anderson classifications were as follows. Of 62 cases of type I fractures, two were infected, and the infection rate was 3.2%. Among those with type II fractures, eight were infected, and the infection rate was 8.2%. Three of 26 cases of type IIIA fracture were infected, yielding an infection rate of 11.5%, seven of 25 cases of type III B fracture were infected (28% infection rate), and one of four cases of type III C fracture was infected (25% infection rate). There was a statistically significant difference between the five groups. Multivariate regression analysis showed that smoking, combined diabetes, surgical time, and fracture Gustilo-Anderson classification were independent risk factors for perioperative infection of open tibial fractures, and the difference in time from injury to first debridement was not related to infection.
conclusionThe incidence of perioperative infection in patients with open tibial fractures has little to do with the time of the first debridement, which is mainly related to the level of the fracture's Gustilo-Anderson classification. At the same time, smoking is prohibited before the operation, the patient's blood glucose is managed, and the debridement operation time is minimized conducive to reducing the incidence of infection.
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