Evidence map›Paper›PMID 32201910›Full record

ArticleClinical pharmacokinetics2020

An Extension of Janmahasatian's Fat-Free Mass Model for Universal Application Across Populations of Different Ethnicities.

Jaydeep Sinha, Hesham S Al-Sallami, Stephen B Duffull

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical pharmacokinetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Jaydeep SinhaSchool of Pharmacy, University of Otago, Dunedin, New Zealand.
Hesham S Al-SallamiSchool of Pharmacy, University of Otago, Dunedin, New Zealand.
Stephen B DuffullSchool of Pharmacy, University of Otago, Dunedin, New Zealand. stephen.duffull@otago.ac.nz.
University of Otago · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFat-free mass (FFM)-based dose scaling is increasingly being adopted in clinical pharmacology. Given the complexities with the measurement of FFM in clinical practice, choosing an appropriate equation for FFM is critical for accurate dose scaling. Janmahasatian's FFM model (FFM

objectiveThe objective of this work was to derive an extended version of the FFM

methodsThe fundamental assumption of FFM

resultsThe parameter estimates (%RSE) of the final FFM

conclusionsAn FFM

Indexed as

Body CompositionEthnicityBody Mass IndexCohort StudiesFemaleHumansMaleModels, Biological

Identifiers

PMID32201910
OpenAlexW3012848249

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.