Evidence map›Paper›PMID 32201674›Full record

ArticleIntractable & rare diseases research2020

Replication study of four keloid-associated polymorphisms in patients of European descent - a single centre study.

Andrzej Dmytrzak, Agnieszka Boroń, Beata Łoniewska, Jeremy S C Clark, Mariusz Kaczmarczyk, Andrzej Ciechanowicz

Abstract read
In one paragraph

Article in Intractable & rare diseases research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. miRSNP rs188493331: A key player in genetic control of microRNA-induced pathway activation in hypertrophic scars and keloids.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andrzej DmytrzakAesthetic Med, Szczecin, Poland.
Agnieszka BorońDepartment of Clinical and Molecular Biochemistry, Pomeranian Medical University, Szczecin, Poland.
Beata ŁoniewskaDepartment of Neonatal Diseases, Pomeranian Medical University, Szczecin, Poland.
Jeremy S C ClarkDepartment of Clinical and Molecular Biochemistry, Pomeranian Medical University, Szczecin, Poland.
Mariusz KaczmarczykDepartment of Clinical and Molecular Biochemistry, Pomeranian Medical University, Szczecin, Poland.
Andrzej CiechanowiczDepartment of Clinical and Molecular Biochemistry, Pomeranian Medical University, Szczecin, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Keloid is defined as a benign dermal fibro-proliferative growth that extends outside the original wound and invades adjacent dermal tissue. Its pathogenesis is complex and much evidence suggests the influence of genetic factors, including the rs873549, rs1511412, rs940187 and rs8032158 polymorphisms associated with keloid risk in Japanese patients. The aim of our study was to investigate possible associations between rs873549, rs1511412, rs940187 and rs8032158 variants and the risk of keloid in Polish patients of European descent. The genetic polymorphisms were identified by sequencing genomic DNA extracted from peripheral blood leukocytes from 86 keloid patients and from newborn cord blood leukocytes from 100 newborns as a control group. No significant differences (

Indexed as

association studyCaucasiansgenetic polymorphismkeloid

Identifiers

PMID32201674
PMCPMC7062593

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.