Evidence map›Paper›PMID 32201535›Full record

ArticleJournal of Cancer2020

Transcriptomic analysis reveals the oncogenic role of S6K1 in hepatocellular carcinoma.

Keng Po Lai, Angela Cheung, Cheuk Hin Ho, Nathan Yi-Kan Tam, Jing Woei Li, Xiao Lin, Ting Fung Chan, Nikki Pui-Yue Lee, Rong Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. RNA-seq analysis reveals transcriptome changes in livers fromBiochemistry and biophysics reports · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Keng Po LaiGuanxi Key Laboratory of Tumor Immunology and Microenvironmental Regulation, Guilin Medical University, Guilin, PR China.
Angela CheungDepartment of Chemistry, City University of Hong Kong, Hong Kong SAR, China.
Cheuk Hin HoDepartment of Chemistry, City University of Hong Kong, Hong Kong SAR, China.
Nathan Yi-Kan TamDepartment of Chemistry, City University of Hong Kong, Hong Kong SAR, China.
Jing Woei LiDepartment of Chemistry, City University of Hong Kong, Hong Kong SAR, China.
Xiao LinSchool of Life Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
Ting Fung ChanSchool of Life Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
Nikki Pui-Yue LeeDepartment of Surgery, University of Hong Kong, Hong Kong SAR, China.
Rong LiGuanxi Key Laboratory of Tumor Immunology and Microenvironmental Regulation, Guilin Medical University, Guilin, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The p70 ribosomal protein S6 kinase 1 (S6K1), a serine/threonine kinase, is commonly overexpressed in a variety of cancers. However, its expression level and functional roles in hepatocellular carcinoma (HCC), which ranks as the third leading cause of cancer-related death worldwide, is still largely unknown. In the current report, we show the

Indexed as

hepatocellular carcinomaproliferationS6K1transcriptometumorigenicity

Identifiers

PMID32201535
PMCPMC7065997

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.