ArticleActa Cardiologica Sinica2020
Beneficial Effects of Hydroalcoholic Extract from
Article in Acta Cardiologica Sinica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- Potential of Fruits to Improve Dyslipidemias: A Pilot Review.Vascular health and risk management · 2025Review
- Identification of Key Hypolipidemic Components and Exploration of the Potential Mechanism of Total Flavonoids fromCurrent issues in molecular biology · 2024Article
- Inhibition of Proliferation and Induction of Apoptosis in Prostatic Carcinoma DU145 Cells by Polysaccharides from YunnanMolecules (Basel, Switzerland) · 2024Article
- Analysis of Volatile Components inMolecules (Basel, Switzerland) · 2023Article
- Recent Advances on Main Active Ingredients, Pharmacological Activities ofFoods (Basel, Switzerland) · 2023Review
- Metabolome combined with gut microbiome revealed the lipid-lowering mechanism of Xuezhiping capsule on hyperlipidemic hamster induced by high fat diet.Frontiers in molecular biosciences · 2023Article
- Article
- Comparative Analysis of Fruit Metabolome Using Widely Targeted Metabolomics Reveals Nutritional Characteristics of DifferentFoods (Basel, Switzerland) · 2022Article
- Control of Obesity, Blood Glucose, and Blood Lipid withJournal of toxicology · 2022Article
- Assessing the Association of Element Imbalances With Arsenism and the Potential Application Value ofFrontiers in pharmacology · 2022Article
- Assessing the Role of Nrf2/GPX4-Mediated Oxidative Stress in Arsenic-Induced Liver Damage and the Potential Application Value of Rosa roxburghii Tratt [Rosaceae].Oxidative medicine and cellular longevity · 2022Article
- Thermally induced isomerization of linoleic acid and α-linolenic acid inFood science & nutrition · 2021Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRosa roxburghii Tratt fruit is extensively used as a medicinal and edible resource in China due to its unique bioactivities. In this research, we aimed to characterize its phenolic acid composition and investigate the potential hypolipidemic effect of this plant in a rat model of hyperlipidemia.
methodsWe evaluated the effects of hydroalcoholic extract of Rosa roxburghii Tratt fruit (HRT) on serum lipids, body weight, activities of lipoprotein metabolism and antioxidant enzymes, and gene expression of lipid metabolism in hyperlipidemic rats.
resultsHRT significantly reduced body weight gain and decreased serum and liver lipid levels in the hyperlipidemic rats. In addition, HRT treatment improved the activities of antioxidant enzymes, lipoprotein lipase, and hepatic lipase, downregulated the mRNA and protein expressions of sterol regulatory element-binding protein 1c and acetyl CoA carboxylase, and upregulated the mRNA and protein expressions of peroxisome proliferator-activated receptor α and low-density lipoprotein receptor in hepatic tissue.
conclusionsThe results showed that Rosa roxburghii Tratt fruit is rich in phenolic acids, and that it exerted lipid lowering effects in the hyperlipidemic rats.
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