Evidence map›Paper›PMID 32201450›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2020

Deep Learning Based High-Resolution Reconstruction of Trabecular Bone Microstructures from Low-Resolution CT Scans using GAN-CIRCLE.

Indranil Guha, Syed Ahmed Nadeem, Chenyu You, Xiaoliu Zhang, Steven M Levy, Ge Wang, James C Torner, Punam K Saha

Open access · greenAbstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Augmenting Osteoporosis Imaging with Machine Learning.Current osteoporosis reports · 2021
    Pooled it
  2. Article
  3. Structure-property relationships in fibrous meniscal tissue through image-based augmentation.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2025
    Article
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  8. Preliminary landscape analysis of deep tomographic imaging patents.Visual computing for industry, biomedicine, and art · 2023
    Review
  9. Review
  10. Class-Aware Adversarial Transformers for Medical Image Segmentation.Advances in neural information processing systems · 2022
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. A Survey on Artificial Intelligence in Pulmonary Imaging.Wiley interdisciplinary reviews. Data mining and knowledge discovery
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Indranil GuhaDepartment of Electrical and Computer Engineering, College of Engineering, University of Iowa, Iowa City, IA 52242.
Syed Ahmed NadeemDepartment of Electrical and Computer Engineering, College of Engineering, University of Iowa, Iowa City, IA 52242.
Chenyu YouDepartment of Computer Science, Yale University, New Haven, CT 05620.
Xiaoliu ZhangDepartment of Electrical and Computer Engineering, College of Engineering, University of Iowa, Iowa City, IA 52242.
Steven M LevyDepartment of Preventive and Community Dentistry, College of Dentistry, University of Iowa, Iowa City, IA 52242.
Ge WangBiomedical Imaging Center, BME/CBIS, Rensselaer Polytechnic Institute, Troy, New York, NY 12180.
James C TornerDepartment of Epidemiology, University of Iowa, Iowa City, IA 52242.
Punam K SahaDepartment of Electrical and Computer Engineering, College of Engineering, University of Iowa, Iowa City, IA 52242.
University of Iowa · USRensselaer Polytechnic Institute · USYale University · US

Funding

CT-Based Modeling of Bone Micro-Architecture and Fracture-Risk in COPDR01HL142042 · NHLBI · UNIVERSITY OF IOWA · PI SAHA, PUNAM K. · 2018 to 2022
$3.5M
NHLBI NIH HHS R01 HL142042
6 · The paper itself

Abstract

Osteoporosis is a common age-related disease characterized by reduced bone density and increased fracture-risk. Microstructural quality of trabecular bone (Tb), commonly found at axial skeletal sites and at the end of long bones, is an important determinant of bone-strength and fracture-risk. High-resolution emerging CT scanners enable

Indexed as

deep learningGAN-CIRCLEhigh-resolution reconstructionmicrostructureosteoporosistrabecular bone

Identifiers

PMID32201450
PMCPMC7085412
OpenAlexW3008930132

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.