Evidence map›Paper›PMID 32200805›Full record

ReviewTrends in cell biology2020

Mitochondrial Functions in Infection and Immunity.

Varnesh Tiku, Man-Wah Tan, Ivan Dikic

Erratum issuedOpen access · hybridAbstract readReview
In one paragraph

Review in Trends in cell biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 203 papers.

0numbers the graph read from it
0cells of the map it votes in
203citing papers in PubMed
17.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

203 citing papers in PubMed, 349 citations in OpenAlex.

  1. Review
  2. Article
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  4. Fecal microbiota transplantation alleviates sepsis-induced acute lung injury by improving mitochondrial function.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2026
    Article
  5. Review
  6. bioRxiv : the preprint server for biology · 2026
    Article
  7. Article
  8. Review
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  11. Article
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  14. Article
  15. Article
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  17. Review
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  19. Article
  20. Review

143 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Varnesh TikuDepartment of Infectious Diseases, Genentech Inc, South San Francisco, USA.
Man-Wah TanDepartment of Infectious Diseases, Genentech Inc, South San Francisco, USA. Electronic address: tan.man-wah@gene.com.
Ivan DikicDepartment of Infectious Diseases, Genentech Inc, South San Francisco, USA; Institute for Biochemistry II. Goethe University Clinic, Frankfurt, Germany. Electronic address: dikic@biochem2.uni-frankfurt.de.
Goethe University Frankfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondria have a central role in regulating a range of cellular activities and host responses upon bacterial infection. Multiple pathogens affect mitochondria dynamics and functions to influence their intracellular survival or evade host immunity. On the other side, major host responses elicited against infections are directly dependent on mitochondrial functions, thus placing mitochondria centrally in maintaining homeostasis upon infection. In this review, we summarize how different bacteria and viruses impact morphological and functional changes in host mitochondria and how this manipulation can influence microbial pathogenesis as well as the host cell metabolism and immune responses.

Indexed as

Immunity, InnateAnimalsCell DeathHumansInfectionsMitochondriaMitochondrial DynamicsSignal Transductionbacteriacell deathinnate immunitymitochondrial metabolismmitochondrial morphologyviruses

Identifiers

PMID32200805
PMCPMC7126537
OpenAlexW3006316914

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.