ArticleJournal of the American Heart Association2020
Association of Heart Rate Variability With Cognitive Performance: The Multi-Ethnic Study of Atherosclerosis.
Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Heart rate variability in relation to cognition and behavior in neurodegenerative diseases: A systematic review and meta-analysis.Ageing research reviews · 2022Pooled it
- Can HRV Biofeedback Training Improve the Mental Resilience of Icelandic Police Officers?Applied psychophysiology and biofeedback · 2025Trial
- The effects of magnesium L-threonate (MagteinFrontiers in nutrition · 2025Trial
- Bidirectional brain-heart interactions in health and disease.Nature reviews. Neurology · 2026Review
- Limited evidence for heart rate variability as a predictor of cognitive and pathophysiological brain markers.Journal of Alzheimer's disease : JAD · 2026Article
- Correlation between epicardial adipose tissue and cognitive performance in older adults. A role for autonomic nervous system imbalance?Frontiers in aging · 2026Article
- Pulse Pressure Impairs Cognition via White Matter Disruption.Hypertension (Dallas, Tex. : 1979) · 2025Article
- Association between long-term visit-to-visit resting heart rate variability and cognitive decline: evidence from two national cohorts.BMC psychiatry · 2025Article
- Heart Rate Variability, Cognitive Performance and Cognitive Impairment in Older Adults: Cross-Sectional Results From the Einstein Aging Study.Health science reports · 2025Article
- Heart rate variability in unstably housed Veterans with mental health conditions.Journal of clinical and experimental neuropsychology · 2025Article
- Fuzzy-Based Sensor Fusion for Cognitive Load Assessment in Inclusive Manufacturing Strategies.Sensors (Basel, Switzerland) · 2025Article
- Cardiac Autonomic Modulation and Cognitive Performance in Community-Dwelling Older Adults: A Preliminary Study.Neurology international · 2025Article
- One-week test-retest recordings of resting cardiorespiratory data for reliability analysis.Scientific data · 2025Article
- Relationship between feedback frequency and task performance: evidence on the mediating role of heart rate.Frontiers in psychology · 2025Article
- Functional data analysis of heart rate variability from continuous ECG monitoring in older adults with and without mild cognitive impairment.Frontiers in aging neuroscience · 2025Article
- Does Heart Rate Variability Predict Impairment of Operational Performance in Divers?Sensors (Basel, Switzerland) · 2024Article
- Prediction model for mild cognitive impairment in patients with type 2 diabetes using the autonomic function test.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Prediction of Mild Cognitive Impairment Status: Pilot Study of Machine Learning Models Based on Longitudinal Data From Fitness Trackers.JMIR formative research · 2024Article
- Review
- Opera trainees' cognitive functioning is associated with physiological stress during performance.Musicae scientiae : the journal of the European Society for the Cognitive Sciences of Music · 2024Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Background Heart rate variability (HRV) is associated with vascular risk factors for dementia, but whether HRV is associated with specific domains of cognitive performance is unclear. Methods and Results In the Multi-Ethnic Study of Atherosclerosis (N=3018; mean age 59.3±9.2 years), we assessed the relationship of 10-second HRV to scores on tests of global cognitive performance (Cognitive Abilities Screening Instrument), processing speed (Digit Symbol Coding), and working memory (Digit Span). HRV was computed as the SD of normal-normal intervals (SDNN) and root mean square of successive differences (RMSSD) at Exam 1 (2000-2002) and Exam 5 (2010-2012). Cognitive tests were administered at Exam 5. We report regression coefficients (β [95% CI]) representing cognitive test score change per 2-fold increase in HRV. After adjustment for age, race/ethnicity, sex, education, apolipoprotein E genotype, and cardiovascular risk factors and incident disease, higher Exam 1 (β=0.37 [0.06, 0.67]) and Exam 5 (β=0.31 [0.04, 0.59]) SDNN were associated with better Cognitive Abilities Screening Instrument performance. Higher Exam 1 (β=0.80 [0.17, 1.43]) and Exam 5 (β=0.63 [0.06, 1.20]) SDNN, and Exam 5 RMSSD (β=0.54 [0.01, 1.08]) were associated with better Digit Symbol Coding performance. Finally, higher Exam 5 SDNN was associated with better Digit Span performance (β=0.17 [0.01, 0.33]). Associations were attenuated after adjustment for resting heart rate. Conclusions Higher HRV is generally associated with better cognitive performance in this multi-ethnic cohort of aging adults, and further study of the relationship of autonomic function to cognition is warranted.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.