Evidence map›Paper›PMID 32200671›Full record

ArticleJournal of neurotrauma2020

Neuroinflammation Mediated by Glia Maturation Factor Exacerbates Neuronal Injury in an

Mohammad Ejaz Ahmed, Govindhasamy Pushpavathi Selvakumar, Duraisamy Kempuraj, Sudhanshu P Raikwar, Ramasamy Thangavel, Kieran Bazley, Kristopher Wu, Osaid Khan, Klaudia Kukulka, Bret Bussinger and 7 more

Open access · greenAbstract read
In one paragraph

Article in Journal of neurotrauma, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Mohammad Ejaz AhmedDepartment of Neurology and School of Medicine, University of Missouri, Columbia, Missouri, USA.
Govindhasamy Pushpavathi SelvakumarDepartment of Neurology and School of Medicine, University of Missouri, Columbia, Missouri, USA.
Duraisamy KempurajDepartment of Neurology and School of Medicine, University of Missouri, Columbia, Missouri, USA.
Sudhanshu P RaikwarDepartment of Neurology and School of Medicine, University of Missouri, Columbia, Missouri, USA.
Ramasamy ThangavelDepartment of Neurology and School of Medicine, University of Missouri, Columbia, Missouri, USA.
Kieran BazleyDepartment of Neurology and School of Medicine, University of Missouri, Columbia, Missouri, USA.
Kristopher WuDepartment of Neurology and School of Medicine, University of Missouri, Columbia, Missouri, USA.
Osaid KhanDepartment of Neurology and School of Medicine, University of Missouri, Columbia, Missouri, USA.
Klaudia KukulkaDepartment of Neurology and School of Medicine, University of Missouri, Columbia, Missouri, USA.
Bret BussingerDepartment of Neurology and School of Medicine, University of Missouri, Columbia, Missouri, USA.
Iuliia DubovaDepartment of Neurology and School of Medicine, University of Missouri, Columbia, Missouri, USA.
Smita ZaheerDepartment of Neurology and School of Medicine, University of Missouri, Columbia, Missouri, USA.
Raghav GovindarajanDepartment of Neurology and School of Medicine, University of Missouri, Columbia, Missouri, USA.
Shankar IyerDepartment of Neurology and School of Medicine, University of Missouri, Columbia, Missouri, USA.
Casey BurtonPhelps Health, Rolla, Missouri, USA.
Donald JamesPhelps Health, Rolla, Missouri, USA.
Asgar ZaheerDepartment of Neurology and School of Medicine, University of Missouri, Columbia, Missouri, USA.
Harry S. Truman Memorial Veterans' Hospital · USUniversity of Missouri · USMissouri University of Science and Technology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traumatic brain injury (TBI) is the primary cause of death and disability affecting over 10 million people in the industrialized world. TBI causes a wide spectrum of secondary molecular and cellular complications in the brain. However, the pathological events are still not yet fully understood. Previously, we have shown that the glia maturation factor (GMF) is a mediator of neuroinflammation in neurodegenerative diseases. To identify the potential molecular pathways accompanying TBI, we used an

Indexed as

AnimalsAstrocytesBrain Injuries, TraumaticCell MovementCells, CulturedGlia Maturation FactorInflammation MediatorsMiceMice, Inbred C57BLMice, KnockoutMicrogliaNeuronsOxidative StressGlia Maturation FactorInflammation Mediatorsezrin/radixin/moesin proteinsglia maturation factorneurodegenerationneuroinflammationtraumatic brain injury

Identifiers

PMID32200671
PMCPMC7336883
OpenAlexW3012777316

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.