Trial reportInternational ophthalmology2020
Comparison of two intense pulsed light patterns for treating patients with meibomian gland dysfunction.
Trial report in International ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02481167 (Evaluation of Meibomian Gland Dysfunction in Chinese Old Patients), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of Meibomian Gland Dysfunction in Chinese Old Patients
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Current application of intense pulsed light for the management of dry eye disease: A systematic review and meta-analysis.Indian journal of ophthalmology · 2024Pooled it
- Technological Interventions for Dry Eye Disease: A Systematic Review and Random-Effects Network Meta-analysis of 3-Month Outcomes.Ophthalmology and therapy · 2026Article
- Mechanisms and Safety of Therapeutic Strategies in Meibomian Gland Dysfunction: A Narrative Review.Ophthalmic research · 2026Review
- Dry Eye Disease Management Via Technological Methods: A Systematic Review and Network Meta-analysis.Ophthalmology and therapy · 2025Article
- Network meta-analysis of different modalities of intense pulsed light therapy in the treatment of dry eye disease induced by meibomian gland dysfunction.Lasers in medical science · 2025Article
- Comparative Analysis of Intense Pulsed Light Therapy in Patients with Meibomian Gland Dysfunction, with and Without Glaucoma Medication.Journal of clinical medicine · 2024Article
- Diamond Bur Microblepharoexfoliation Combined with Intense Pulse Light and Meibomian Gland Expression for Evaporative Dry Eye: A Short-term Controlled Clinical Trial.Ophthalmology and therapy · 2024Article
- Article
- Intense pulsed-light treatment improves objective optical quality in patients with meibomian gland dysfunction.BMC ophthalmology · 2023Article
- Therapeutic efficacy of optimal pulse technology in the treatment ofFrontiers in medicine · 2023Article
- Comparison of Intense Pulsed Light Therapy on Patients with Meibomian Gland Dysfunction Using AQUA CEL and M22 Devices.Journal of clinical medicine · 2022Article
- Intense pulsed light-based treatment for the improvement of symptoms in glaucoma patients treated with hypotensive eye drops.Eye and vision (London, England) · 2022Article
- Pulsed Light Therapy in the Management of Dry Eye Disease: Current Perspectives.Clinical ophthalmology (Auckland, N.Z.) · 2022Review
- Low-Level Light Therapy in Association with Intense Pulsed Light for Meibomian Gland Dysfunction.Clinical ophthalmology (Auckland, N.Z.) · 2022Article
- Indirect Application of Intense Pulsed Light Induces Therapeutic Effects on Experimental Murine Meibomian Gland Dysfunction.Frontiers in medicine · 2022Article
- Characterization and Prediction of the Clinical Outcome of Intense Pulsed Light-Based Treatment in Dry Eye Associated to Meibomian Gland Dysfunction.Journal of clinical medicine · 2021Article
- Therapeutic Instruments Targeting Meibomian Gland Dysfunction.Ophthalmology and therapy · 2020Review
- Use of Intense Pulsed Light to Mitigate Meibomian Gland Dysfunction for Dry Eye Disease.International journal of medical sciences · 2020Review
- Current practices and considerations in intense pulsed light therapy for meibomian gland dysfunction.Taiwan journal of ophthalmologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
purposeThe objective of this was to determine the efficacy of different patterns of intense pulsed light (IPL) therapy in patients with meibomian gland dysfunction (MGD). MATERIALS AND
methodIPL treatment was administered in 124 eyes of 62 patients with MGD-associated dry eye disease (DED). These patients were divided randomly into two groups treated with different IPL patterns. The first group was treated with "Optimal Pulse Technology" (OPT) (n = 29) and received three consecutive treatments (10-14 J/cm
resultsCompared to baseline, the clinical symptoms and signs in both groups were significantly improved at one and three months after IPL treatment. However, compared to the IRPL group, the OPT-treated group showed significant improvement in the clarity of MG secretions (P = 0.001), the number of MGs yielding clear or cloudy liquid secretions (P < 0.001), the total MG secretion score (P < 0.001) in lower eyelid, the lid margin score in upper (P < 0.001) and lower eyelids (P = 0.013), the first NIKBUT (P = 0.009), and FTBUT (P = 0.006).
conclusionsThese results suggest that IPL has significant clinical value in treating patients with MGD. OPT IPL treatment was more effective in improving MG function in lower eyelids and partial tear film signs than IRPL IPL treatment.
trial registrationThe study was registered at www.clinicaltrials.gov, and the clinical trial accession number is NCT02481167.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.