Evidence map›Paper›PMID 32200495›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2020

Contactless treatment for scoliosis by electromagnetically controlled shape-memory alloy rods: a preliminary study in rabbits.

Zhiqiang Hou, Zhibo Liu, Xiaobin Zhu, Yuanlong Xie, Feifei Yan, Hao Yin, Zeheng Zhang, Minhao Wu, Xiaoxiao Liang, Zhouming Deng and 9 more

Abstract read
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In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Current benchtop protocols are not appropriate for the evaluation of distraction-based growing rods: a literature review to justify a new protocol and its development.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 2 institutions in 2 countries.

Zhiqiang HouDepartment of Orthopaedics, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.
Zhibo LiuDepartment of Orthopaedics, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.
Xiaobin ZhuDepartment of Orthopaedics, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China. zxbrobin@hotmail.com.
Yuanlong XieDepartment of Orthopaedics, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.
Feifei YanDepartment of Orthopaedics, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.
Hao YinSchool of Civil Engineering, Wuhan University, Wuhan, People's Republic of China.
Zeheng ZhangElectronic Information School of Wuhan University, Wuhan, People's Republic of China.
Minhao WuDepartment of Orthopaedics, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.
Xiaoxiao LiangDepartment of Orthopaedics, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.
Zhouming DengDepartment of Orthopaedics, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.
Chao HuDepartment of Orthopaedics, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.
Kangwen XiaoDepartment of Orthopaedics, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.
Shiliang ChenDepartment of Orthopaedics, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.
Yan ChenDepartment of Orthopaedics, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.
Zheyu WuDepartment of Orthopaedics, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.
Xudong GuElectronic Information School of Wuhan University, Wuhan, People's Republic of China.
Qingping SunDepartment of Mechanical and Aerospace Engineering, The Hong Kong University of Science and Technology, Hong Kong, People's Republic of China.
Binbin NiElectronic Information School of Wuhan University, Wuhan, People's Republic of China.
Lin CaiDepartment of Orthopaedics, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China. orthopedics@whu.edu.cn.
Wuhan University · CNHong Kong University of Science and Technology · HK

Funding

Department of Science and Technology, Hubei Provincial People's Government 2017ACA098Health Care of Yellow Crane Talent Plan of Wuhan City Grant No. 17Wuhan University znpy2016055
6 · The paper itself

Abstract

purposeTo evaluate the safety and efficacy of a system aiming to correct scoliosis called "electromagnetically controlled shape-memory alloy rods" (EC-SMAR) used in a rabbit model.

methodsWe heat-treated shape-memory alloy (SMA) rods to achieve a transition temperature between 34 and 47 °C and a C-shape austenite phase. We then developed a water-cooled generator capable of generating an alternating magnetic field (100 kHz) for induction heating. We next studied the efficacy of this system in vitro and determined some parameters prior to proceeding with animal experiments. We then employed a rabbit model, in which we fixed a straight rod along the spinous processes intraoperatively, and conducted induction heating postoperatively every 4 days for 1 month, while performing periodic X-ray assessments.

resultsSignificant kyphotic deformations with Cobb angles of about 45° (p < 0.01) were created in five rabbits, and no complications occurred throughout the experiment. The rabbits are still very much alive and do not show any signs of discomfort.

conclusionsThis is the first system that can modulate spinal deformation in a gradual, contactless, noninvasive manner through electromagnetic induction heating applied to SMA alloy rods. Although this study dealt with healthy spines, it provides promising evidence that this device also has the capacity to correct human kyphosis and even scoliosis in the future. These slides can be retrieved under Electronic Supplementary Material.

Indexed as

ScoliosisShape Memory AlloysAlloysAnimalsNickelRabbitsSpineTitaniumAlloysNickelShape Memory AlloysTitaniumContactlessElectromagnetic induction heatingKyphosisNickel titanium (NiTi)ScoliosisShape-memory alloy (SMA)

Identifiers

PMID32200495
OpenAlexW3011026996

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.