Evidence map›Paper›PMID 32199771›Full record

ArticleJournal of diabetes and its complications2020

Consuming a ketogenic diet leads to altered hypoglycemic counter-regulation in mice.

Christopher D Morrison, Cristal M Hill, Marina A DuVall, Carolyn E Coulter, Jasmin L Gosey, Matthew J Herrera, Lauren E Maisano, Hunter X Sikaffy, David H McDougal

Open access · greenAbstract read
In one paragraph

Article in Journal of diabetes and its complications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
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  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Dietary Energy Partition: The Central Role of Glucose.International journal of molecular sciences · 2020
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Christopher D MorrisonPennington Biomedical Research Center, Baton Rouge, LA 70808, USA.
Cristal M HillPennington Biomedical Research Center, Baton Rouge, LA 70808, USA.
Marina A DuVallPennington Biomedical Research Center, Baton Rouge, LA 70808, USA.
Carolyn E CoulterPennington Biomedical Research Center, Baton Rouge, LA 70808, USA.
Jasmin L GoseyPennington Biomedical Research Center, Baton Rouge, LA 70808, USA.
Matthew J HerreraPennington Biomedical Research Center, Baton Rouge, LA 70808, USA.
Lauren E MaisanoPennington Biomedical Research Center, Baton Rouge, LA 70808, USA.
Hunter X SikaffyPennington Biomedical Research Center, Baton Rouge, LA 70808, USA.
David H McDougalPennington Biomedical Research Center, Baton Rouge, LA 70808, USA. Electronic address: David.McDougal@pbrc.edu.
Pennington Biomedical Research Center · US

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2012 to 2026
$69.1M
FGF21 is an endocrine signal of protein restrictionR01DK105032 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI MORRISON, CHRISTOPHER D · 2016 to 2019
$1.4M
NIDDK NIH HHS R01 DK105032NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

Ketogenic diets (KDs) are becoming increasingly popular for the treatment of diabetes, yet they are associated with increased frequency of hypoglycemia. Here we report that mice fed a KD display blunted glucagon release to hypoglycemia and neuroglucopenia, suggesting that consuming a KD may increase the risk for iatrogenic hypoglycemia.

Indexed as

AnimalsBlood GlucoseCerebrumCorticosteroneDiet, KetogenicDisease Models, AnimalFeedback, PhysiologicalGlucagonGlucoseHypoglycemiaMaleMiceMice, Inbred C57BLRisk FactorsBlood GlucoseCorticosteroneGlucagonGlucoseDiabetes complicationsHypoglycemiaKetosis

Identifiers

PMID32199771
PMCPMC7299499
OpenAlexW3004429806

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.