Evidence map›Paper›PMID 32199542›Full record

ArticleJournal of substance abuse treatment2020

Hospitalization outcomes of people who use drugs: One size does not fit all.

Elisabeth Merchant, Deirdre Burke, Leah Shaw, Hansel Tookes, Dustin Patil, Joshua A Barocas, Alysse G Wurcel

Open access · greenAbstract read
In one paragraph

Article in Journal of substance abuse treatment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 41 citations in OpenAlex.

  1. Trial
  2. Methamphetamine use and illicit opioid use during buprenorphine treatment.Journal of substance use and addiction treatment · 2023
    Trial
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  17. Shifting North American drug markets and challenges for the system of care.International journal of mental health systems · 2021
    Article
  18. Against Medical Advice Discharges in Injection and Non-injection Drug Use-associated Infective Endocarditis: A Nationwide Cohort Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  19. Evaluating Differences in Opioid and Stimulant Use-associated Infectious Disease Hospitalizations in Florida, 2016-2017.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Elisabeth MerchantDepartment of Medicine, Tufts Medical Center, Boston, MA, United States of America.
Deirdre BurkeDivision of Geographic Medicine and Infectious Diseases, Department of Medicine Tufts Medical Center, United States of America.
Leah ShawDivision of Geographic Medicine and Infectious Diseases, Department of Medicine Tufts Medical Center, United States of America.
Hansel TookesDepartment of Medicine, Division of Infectious Diseases, University of Miami, Miami, FL, United States of America.
Dustin PatilDepartment of Psychiatry, Tufts Medical Center, United States of America.
Joshua A BarocasBoston University School of Medicine, Boston, MA, United States of America; Boston Medical Center, Boston, MA, United States of America.
Alysse G WurcelDivision of Geographic Medicine and Infectious Diseases, Department of Medicine Tufts Medical Center, United States of America; Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, United States of America. Electronic address: awurcel@tuftsmedicalcenter.org.
Tufts Medical Center · USBoston Medical Center · USTufts University · USUniversity of Miami · US

Funding

CTSA Institutional Mentored Career Development Program (KL2)KL2TR002545 · NCATS · TUFTS UNIVERSITY BOSTON · PI FREUND, KAREN · 2018 to 2022
$5.0M
NCATS NIH HHS KL2 TR002545
6 · The paper itself

Abstract

People with opioid use disorder (OUD) have worse hospital outcomes and higher healthcare costs. There are rising reports of people with OUD also using other classes of drugs, however patterns of substance use have not been evaluated for differential effects on hospital outcomes. We performed a data-analysis of the Healthcare Utilization Project's National Readmissions Database, examining the effects of patterns of substance use, age, gender, and diagnosis on the outcomes of Against Medical Advice (AMA) discharges and 30-day readmissions. About one-third of the patients with OUD who were admitted to the hospital had at least one additional substance use disorder (SUD). Thirteen percent of persons with OUD were discharged AMA, and 12% were readmitted to the hospital within 30 days of discharge. Compared to people with OUD alone, people who used stimulants had increased odds of AMA discharge (aOR 1.83 (CI 1.73, 1.96)) and 30-day readmission (aOR 1.30 (95% CI 1.23, 1.37)). Multiple concomitant substance use disorders were associated with increased odds of AMA discharge and 30-day readmission. Conclusions: People with OUD have high rates of both AMA discharges and 30 day-readmissions, and there is a layered effect of increasing co-occurring SUDs leading to worse hospitalization outcomes. The heterogeneity of drug use patterns needs to be considered when developing strategies to improve health care outcomes for people with substance use disorder.

Indexed as

HospitalizationPharmaceutical PreparationsHumansPatient DischargePatient ReadmissionRetrospective StudiesPharmaceutical Preparations

Identifiers

PMID32199542
PMCPMC7089869
OpenAlexW3001065379

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.