ArticleBMC oral health2020
Ca
Article in BMC oral health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 52 citations in OpenAlex.
- Caries-preventing effect of a hydroxyapatite-toothpaste in adults: a 18-month double-blinded randomized clinical trial.Frontiers in public health · 2023Trial
- Efficacy of a Toothpaste Based on Microcrystalline Hydroxyapatite on Children with Hypersensitivity Caused by MIH: A Randomised Controlled Trial.Oral health & preventive dentistry · 2021Trial
- Impact of a toothpaste with microcrystalline hydroxyapatite on the occurrence of early childhood caries: a 1-year randomized clinical trial.Scientific reports · 2021Trial
- Article
- Development and characterization of a multifunctional alginate-chitosan hydrogel incorporating nano-hydroxyapatite andBiomaterials and biosystems · 2026Article
- CD44-Targeting Hydroxyapatite Nanoparticles (HAP) Induce Mitochondrial Dysfunction-Driven PANoptosis and Immunogenic Cell Death (ICD) via Ca Overload in Colorectal Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Efficacy of calcium hypophosphite toothpaste in remineralizing initial caries in vitro.BMC oral health · 2026Article
- Calcium Hypophosphite: A New Active Ingredient for Biomimetic Oral Care.Biomimetics (Basel, Switzerland) · 2026Review
- Remineralization of early caries lesions by calcium hypophosphite in vitro: a surface microhardness study.BDJ open · 2026Article
- In vitro study on the neutralization potential of particulate hydroxyapatite in erosive acids.BDJ open · 2026Article
- Comparison of the Caries Remineralizing Effects of Dentifrices Based on Natural Hydroxyapatite, Synthetic Hydroxyapatite, and Fluoride: A pH Cycling Study.Biomimetics (Basel, Switzerland) · 2026Article
- Fluoride-Free Toothpastes for Caries Prevention: A Systematic Review of Clinical Evidence on Active Ingredients.Clinical, cosmetic and investigational dentistry · 2026Review
- Impact of demineralization, brushing, and remineralization sequences on dentin mineral retention and surface properties.Odontology · 2025Article
- Nano-Hydroxyapatite-Based Mouthwash for Comprehensive Oral Care: Activity Against Bacterial and Fungal Pathogens with Antioxidant and Anti-Inflammatory Action.Materials (Basel, Switzerland) · 2025Article
- Antimicrobial and Antibiofilm Properties of Hydroxyapatite/Nano-Hydroxyapatite in Preventing Dental Caries: A Systematic Review.European journal of dentistry · 2025Article
- Efficacy of Biomimetic Hydroxyapatite in the Treatment of Extrinsic Dental Stains in Smokers and Non-Smokers.Materials (Basel, Switzerland) · 2025Article
- Evaluation of the Efficacy of a Dentifrice Tablet to Prevent Dental Caries: A Microbial Study.Dentistry journal · 2025Article
- The Role of Crosslinking Agents in the Development of Collagen-Hydroxyapatite Composite Materials for Bone Tissue Engineering.Materials (Basel, Switzerland) · 2025Article
- A novel stable biomimetic adhesive coating for functionalization of orthodontic brackets against bacterial colonization and white spot lesions.BMC oral health · 2025Article
- Advancements in nanohydroxyapatite: synthesis, biomedical applications and composite developments.Regenerative biomaterials · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundSynthetic particulate hydroxyapatite (HAP; Ca
methodsPlanktonic cultures of S. mutans were grown in BHI broth with 1% sucrose or with additional 5% HAP or 5% silica for up to 48 h. Separately, biofilms of S. mutans were grown in BHI for 72 h in total. After 24 h of this biofilm culture, either BHI alone or BHI with additional 0.5% HAP or 0.5% silica was added. After 48 h, BHI with 1% sucrose was added to allow bacterial acid formation. Ca
resultsRelevant release of Ca
conclusionsUnder the tested conditions, synthetic HAP releases Ca
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.