Evidence map›Paper›PMID 32199289›Full record

ArticleiScience2020

Inositol 1,4,5-Trisphosphate Receptor Type 3 Regulates Neuronal Growth Cone Sensitivity to Guidance Signals.

Carmen Chan, Noriko Ooashi, Hiroki Akiyama, Tetsuko Fukuda, Mariko Inoue, Toru Matsu-Ura, Tomomi Shimogori, Katsuhiko Mikoshiba, Hiroyuki Kamiguchi

Open access · goldAbstract read
In one paragraph

Article in iScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Potential Roles of IPBiomolecules · 2024
    Review
  2. Article
  3. A Role for Second Messengers in Axodendritic Neuronal Polarity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Review
  4. Chaperone Sigma1R and Antidepressant Effect.International journal of molecular sciences · 2020
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Carmen ChanRIKEN Center for Brain Science, 2-1 Hirosawa, Wako City, Saitama 351-0198, Japan.
Noriko OoashiRIKEN Center for Brain Science, 2-1 Hirosawa, Wako City, Saitama 351-0198, Japan.
Hiroki AkiyamaAdvanced Research Center for Human Sciences, Waseda University, Tokorozawa, Saitama 359-1192, Japan.
Tetsuko FukudaRIKEN Center for Brain Science, 2-1 Hirosawa, Wako City, Saitama 351-0198, Japan.
Mariko InoueRIKEN Center for Brain Science, 2-1 Hirosawa, Wako City, Saitama 351-0198, Japan.
Toru Matsu-UraDepartment of Stem Cell Pathology, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka 573-1010, Japan.
Tomomi ShimogoriRIKEN Center for Brain Science, 2-1 Hirosawa, Wako City, Saitama 351-0198, Japan.
Katsuhiko MikoshibaShanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai 201210, China.
Hiroyuki KamiguchiRIKEN Center for Brain Science, 2-1 Hirosawa, Wako City, Saitama 351-0198, Japan. Electronic address: hiroyuki.kamiguchi@riken.jp.
RIKEN Center for Brain Science · JPKansai Medical University · JPShanghaiTech University · CNWaseda University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During neurodevelopment, the growth cone deciphers directional information from extracellular guidance cues presented as shallow concentration gradients via signal amplification. However, it remains unclear how the growth cone controls this amplification process during its navigation through an environment in which basal cue concentrations vary widely. Here, we identified inositol 1,4,5-trisphosphate (IP

Indexed as

Biological SciencesCellular NeuroscienceMolecular NeuroscienceNeuroscience

Identifiers

PMID32199289
PMCPMC7082556
OpenAlexW3009999788

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.