Evidence map›Paper›PMID 32199285›Full record

ArticleNeuroImage. Clinical2020

Resting-state EEG topographies: Reliable and sensitive signatures of unilateral spatial neglect.

Elvira Pirondini, Nurit Goldshuv-Ezra, Nofya Zinger, Juliane Britz, Nachum Soroker, Leon Y Deouell, Dimitri Van De Ville

Abstract read
In one paragraph

Article in NeuroImage. Clinical, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elvira PirondiniInstitute of Bioengineering/Center for Neuroprosthetics, Ecole Polytechnique Federale de Lausanne (EPFL), Lausanne, Switzerland; Department of Radiology and Medical Informatics, University of Geneva, Geneva, Switzerland. Electronic address: elvira.pirondini@epfl.ch.
Nurit Goldshuv-EzraDepartment of Neurological Rehabilitation, Loewenstein Rehabilitation Hospital, Raanana, Israel; Evoked Potentials Laboratory, Technion - Israel Institute of Technology, Haifa, Israel.
Nofya ZingerDepartment of Psychology and Edmond and Lily Safra Center for Brain Sciences (ELSC), The Hebrew University of Jerusalem, Israel.
Juliane BritzDepartment of Psychology and Neurology Unit, Medicine Section, Faculty of Science and Medicine, University of Fribourg, Fribourg 1700, Switzerland.
Nachum SorokerDepartment of Neurological Rehabilitation, Loewenstein Rehabilitation Hospital, Raanana, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Leon Y DeouellDepartment of Psychology and Edmond and Lily Safra Center for Brain Sciences (ELSC), The Hebrew University of Jerusalem, Israel. Electronic address: leon.deouell@mail.huji.ac.il.
Dimitri Van De VilleInstitute of Bioengineering/Center for Neuroprosthetics, Ecole Polytechnique Federale de Lausanne (EPFL), Lausanne, Switzerland; Department of Radiology and Medical Informatics, University of Geneva, Geneva, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Theoretical advances in the neurosciences are leading to the development of an increasing number of proposed interventions for the enhancement of functional recovery after brain damage. Integration of these novel approaches in clinical practice depends on the availability of reliable, simple, and sensitive biomarkers of impairment level and extent of recovery, to enable an informed clinical-decision process. However, the neuropsychological tests currently in use do not tap into the complex neural re-organization process that occurs after brain insult and its modulation by treatment. Here we show that topographical analysis of resting-state electroencephalography (rsEEG) patterns using singular value decomposition (SVD) could be used to capture these processes. In two groups of subacute stroke patients, we show reliable detection of deviant neurophysiological patterns over repeated measurement sessions on separate days. These patterns generalized across patients groups. Additionally, they maintained a significant association with ipsilesional attention bias, discriminating patients with spatial neglect of different severity levels. The sensitivity and reliability of these rsEEG topographical analyses support their use as a tool for monitoring natural and treatment-induced recovery in the rehabilitation process.

Indexed as

AgedBrainElectroencephalographyFemaleHumansMaleMiddle AgedPerceptual DisordersReproducibility of ResultsSignal Processing, Computer-AssistedStrokeComputer-enhanced measurement, EEG analysisEEG topography featuresMachine learningOutcome measurementRehabilitationResting-state EEG biomarkersStrokeUnilateral spatial neglect

Identifiers

PMID32199285
PMCPMC7083886

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.