ArticleChromosoma1988
DNA cloning and amino acid sequence determination of a major constituent protein of mammalian nucleoli. Correspondence of the nucleoplasmin-related protein NO38 to mammalian protein B23.
Article in Chromosoma, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 84 citations in OpenAlex.
- Nucleophosmin Protein Dephosphorylation by DUSP3 Is a Fine-Tuning Regulator of p53 Signaling to Maintain Genomic Stability.Frontiers in cell and developmental biology · 2021Article
- Posttranscriptional regulation of chicken ccn2 gene expression by nucleophosmin/B23 during chondrocyte differentiation.Molecular and cellular biology · 2008Article
- Interaction between Agrobacterium tumefaciens oncoprotein 6b and a tobacco nucleolar protein that is homologous to TNP1 encoded by a transposable element of Antirrhinum majus.Journal of plant research · 2008Article
- Centromeric protein bodies on avian lampbrush chromosomes contain a protein detectable with an antibody against DNA topoisomerase II.Chromosoma · 2004Article
- ARF impedes NPM/B23 shuttling in an Mdm2-sensitive tumor suppressor pathway.Molecular and cellular biology · 2004Article
- Overexpression of the nucleolar protein nucleophosmin/B23 in collagen lattice-cultured fibroblasts: potential role in the control of protein synthesis.Molecular and cellular biochemistry · 2002Article
- Conventional and nonconventional roles of the nucleolus.International review of cytology · 2002Review
- Cloning, expression and nuclear localization of human NPM3, a member of the nucleophosmin/nucleoplasmin family of nuclear chaperones.BMC genomics · 2001Article
- Elevated MLF1 expression correlates with malignant progression from myelodysplastic syndrome.Leukemia · 2000Article
- cDNA cloning, expression pattern, and chromosomal localization of Mlf1, murine homologue of a gene involved in myelodysplasia and acute myeloid leukemia.The American journal of pathology · 1999Article
- Apoptosis induced by the myelodysplastic syndrome-associated NPM-MLF1 chimeric protein.Oncogene · 1999Article
- Gadd45, a p53-responsive stress protein, modifies DNA accessibility on damaged chromatin.Molecular and cellular biology · 1999Article
- Nucleophosmin-anaplastic lymphoma kinase of large-cell anaplastic lymphoma is a constitutively active tyrosine kinase that utilizes phospholipase C-gamma to mediate its mitogenicity.Molecular and cellular biology · 1998Article
- Identification of a small, very acidic constitutive nucleolar protein (NO29) as a member of the nucleoplasmin family.Proceedings of the National Academy of Sciences of the United States of America · 1997Article
- Role of the nucleophosmin (NPM) portion of the non-Hodgkin's lymphoma-associated NPM-anaplastic lymphoma kinase fusion protein in oncogenesis.Molecular and cellular biology · 1997Article
- Topogenesis of a nucleolar protein: determination of molecular segments directing nucleolar association.Molecular biology of the cell · 1997Article
- GTP gamma S restores nucleophosmin (NPM) localization to nucleoli of GTP-depleted HeLa cells.Molecular and cellular biochemistry · 1995Article
- Translocation of nucleophosmin from nucleoli to nucleoplasm requires ATP.The Biochemical journal · 1995Article
- The yeast NOP4 gene product is an essential nucleolar protein required for pre-rRNA processing and accumulation of 60S ribosomal subunits.The EMBO journal · 1994Article
- Identification of the MAGE-1 gene product by monoclonal and polyclonal antibodies.Proceedings of the National Academy of Sciences of the United States of America · 1994Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Using a cDNA probe encoding the nucleolar protein NO38 of Xenopus laevis, we have isolated clones that code for the corresponding mammalian protein from cDNA libraries of mouse embryonal carcinoma and fetal liver cells. The murine cDNA-derived amino acid sequence defines a polypeptide of 292 amino acids (including the initial methionine) of a total molecular weight of 32,560 and identifies a single approximately 1.5 kb mRNA on Northern blot hybridization. This polypeptide, which is highly homologous to the Xenopus protein NO38, displays an organization in three major domains: (1) an aminoterminal portion of 119 amino acids, which shows a striking homology to nucleoplasmin of Xenopus; (2) a central portion of 68 amino acids that contains two extended acidic domains, a shorter of 13 residues and a longer of 29 residues, separated by an interval enriched in positively charged amino acids; (3) a carboxyterminal portion of 105 amino acids, which is almost identical to the reported partial amino acid sequence of human and rat nucleolar protein termed B23. The sequence comparisons show that the murine protein is the mammalian counterpart to the nucleolar protein NO38 of Xenopus and is compatible with the idea that both proteins NO38 represent the amphibian and murine equivalents to the human and rat nucleolar phosphoprotein B23. Special sequence features and predicted conformations of this protein are discussed in relation to the specific localization and the possible functions of this major nucleolar protein.
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