Observational studyIndian pediatrics2020
Association of Early-Onset Sepsis and Vitamin D Deficiency in Term Neonates.
Observational study in Indian pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.
- Assessment of the influence of vitamin D in patients with sepsis: a systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- Vitamin D status was associated with sepsis in critically ill children: A PRISMA compliant systematic review and meta-analysis.Medicine · 2021Pooled it
- Vitamin D and Neonatal Sepsis: Current Evidence, Biological Mechanisms, and Future Directions-A Scoping Review.Nutrients · 2026Article
- Article
- Association Between Vitamin D Deficiency and Sepsis in Term Neonates: A Case-Control Study.Cureus · 2024Article
- A Prospective Cross-Sectional Study on the Vitamin D Status of Neonates and the Impact of Neonates' Standard Vitamin D Supplementation on Neonatal Morbidities.Children (Basel, Switzerland) · 2024Article
- Vitamin D Deficiency: An Underestimated Factor in Sepsis?International journal of molecular sciences · 2023Review
- Vitamin D Deficiency: Definition Matters!Indian pediatrics · 2020Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine if vitamin D status is affected in term neonates with early onset sepsis and its association with outcome.
methodsStudy was done at a level 3 neonatal unit on 140 neonates. Term neonates with early onset sepsis (study group, 70 patients) and without sepsis (control group, 70 patients) were enrolled.
resultsMean neonatal vitamin D level in the study group was 16.00 (10.49) ng/mL and in the control group, was 29.07(8.36) ng/mL (P =0.061). In the study group 80% (n=56) babies had low vitamin D levels (<32 ng/mL) among whom 51.7% (n=29) had severe vitamin D deficiency (<11ng/mL). In the control group, 58.5% (n=41) had low vitamin D levels of whom, 9.8% (n=4) had severe vitamin D deficiency (P<0.001 and P<0.001, respectively). Mortality and highly probable sepsis were more common with vitamin D levels <11ng/mL in the study group (P= 0.005 and P=0.006, respectively).
conclusionsVitamin D is deficient in neonates with early onset sepsis and is associated with increased sepsis severity and mortality.
Indexed as
Identifiers
32198863W3012566803What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.