ArticleIndian pediatrics2020
Clinical Profile of Critical Pertussis in Children at a Pediatric Intensive Care Unit in Northern India.
Article in Indian pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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The trial behind it
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Variability in the Diagnostic Criteria for Severe Pertussis: A Systematic Review.JAMA network open · 2026Pooled it
- Pertussis infection in critically ill infants: meta-analysis and validation of a mortality score.Critical care (London, England) · 2025Pooled it
- Clinical Profile, Outcome and Risk Factors for Mortality Among Children Admitted with Critical Pertussis: An Ambispective Study.Indian pediatrics · 2026Article
- Clinical characteristics and risk factors for severe pertussis in infants aged less than 3 months.Translational pediatrics · 2026Article
- Early venoarterial extracorporeal membrane oxygenation with airway clearance techniques in severe pertussis with pulmonary hypertension in a two-month-old infant: a case report.International journal of emergency medicine · 2026Article
- Clinical characteristics of pertussis in infants and risk factors for respiratory support.Annals of medicine · 2025Article
- Clinical and Epidemiological Characteristics of Pediatric Pertussis Cases: A Retrospective Study from Southeast Romania.Antibiotics (Basel, Switzerland) · 2025Article
- Critical pertussis infection in the paediatric intensive care unit: A case series in an outbreak.The Southern African journal of critical care : the official journal of the Critical Care Society · 2025Article
- Severe pertussis in infants: a scoping review.Annals of medicine · 2024Article
- Evaluation of Pertussis Disease in Young Infants in India: A Hospital-Based Multicentric Observational Study.Indian journal of pediatrics · 2024Observational
- [Research advances in the treatment strategies for severe pertussis in children].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021Review
- Herbal Medicine-Induced Seizures in Children: Single-Center Experience Over 18 Months.Indian pediatrics · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectiveTo delineate the clinical profile, complications, intensive care needs, and predictors of mortality in children with critical pertussis.
methodsRetrospective analysis of case records of children in the pediatric intensive care unit of a tertiary-care hospital, with a diagnosis of critical pertussis over 3 years. Diagnostic criteria included CDC case definition and confirmation by polymerase chain reaction (PCR), when available. Survivors and non-survivors were compared to identify predictors of mortality.
results36 records were analysed, most cases were infants (31, 86.1%). 10 (27.7%) were (below 6 weeks of age). In the rest, 16 (61.5%) were partially immunized or unimmunized against pertussis. Rapid breathing (88.9%), paroxysmal cough (86.1%) and apnea (41.7%) were common presenting complaints. Hypoxemia (97.2%), hyperleukocytosis (61.1%) and encephalopathy (52.8%) were common complications. Intensive care needs were mechanical ventilation in 11 (30.6%), vasoactive support in 7 (19.4%) and exchange transfusion in 3 (8.3%). Female gender, apnea, hyperleukocytosis, encephalopathy, need for vasoactive support, and mechanical ventilation predicted mortality.
conclusionsPertussis demands attention due to its varied presentation, increased complications and higher mortality.
Indexed as
Identifiers
32198862PMC7223409What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.