Evidence map›Paper›PMID 32198834›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2020

Case report of COVID-19 in a kidney transplant recipient: Does immunosuppression alter the clinical presentation?

Elena Guillen, Gaston J Pineiro, Ignacio Revuelta, Diana Rodriguez, Marta Bodro, Asunción Moreno, Josep M Campistol, Fritz Diekmann, Pedro Ventura-Aguiar

Registry-linked trialAbstract readCase Reports
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04494776 (Severe Acute Respiratory Syndrome Coronavirus 2), which is not on this map. Cited by 164 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
164citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04494776 recruitingnot on this map

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) Infection (COVID-19) in Kidney Transplant Recipients: a Brazilian Multicenter Study

TypeobservationalSponsorHelio Tedesco Silva JuniorRan2020 to 2025Enrolled500ConditionsSARS-CoV-2 Infection, Kidney Transplant Infection
3 · Its place in the literature

Who cites it

164 citing papers in PubMed, 11 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Effect of immunosuppression maintenance in solid organ transplant recipients with COVID-19: Systematic review and meta-analysis.Transplant infectious disease : an official journal of the Transplantation Society · 2021
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  7. COVID-19 clinical manifestations and treatment strategies among solid-organ recipients: A systematic review of cases.Transplant infectious disease : an official journal of the Transplantation Society · 2020
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  12. Article
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  16. Review
  17. Severe COVID-19 in 2 Kidney Transplant Patients in Gabon.The American journal of case reports · 2022
    Article
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  19. Review
  20. Article

104 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Elena GuillenDepartment of Nephrology and Kidney Transplantation, Hospital Clinic Barcelona, Barcelona, Spain.
Gaston J PineiroDepartment of Nephrology and Kidney Transplantation, Hospital Clinic Barcelona, Barcelona, Spain.
Ignacio RevueltaDepartment of Nephrology and Kidney Transplantation, Hospital Clinic Barcelona, Barcelona, Spain.
Diana RodriguezDepartment of Nephrology and Kidney Transplantation, Hospital Clinic Barcelona, Barcelona, Spain.
Marta BodroDepartment of Infectious Diseases, Hospital Clinic Barcelona, Barcelona, Spain.
Asunción MorenoDepartment of Infectious Diseases, Hospital Clinic Barcelona, Barcelona, Spain.
Josep M CampistolDepartment of Nephrology and Kidney Transplantation, Hospital Clinic Barcelona, Barcelona, Spain.
Fritz DiekmannDepartment of Nephrology and Kidney Transplantation, Hospital Clinic Barcelona, Barcelona, Spain.ORCID https://orcid.org/0000-0001-6199-3016
Pedro Ventura-AguiarDepartment of Nephrology and Kidney Transplantation, Hospital Clinic Barcelona, Barcelona, Spain.ORCID https://orcid.org/0000-0003-3381-7503

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 is novel infectious disease with an evolving understanding of its epidemiology and clinical manifestations. Immunocompromised patients often present atypical presentations of viral diseases. Herein we report a case of a COVID-19 infection in a solid organ transplant recipient, in which the first clinical symptoms were of gastrointestinal viral disease and fever, which further progressed to respiratory symptoms in 48 hours. In these high risk populations, protocols for screening for SARS-Cov2 may be needed to be re-evaluated.

Indexed as

Immunocompromised HostImmunosuppression TherapyKidney TransplantationBetacoronavirusCoronavirus InfectionsCOVID-19Glomerulonephritis, IGAHumansImmune ToleranceKidney Failure, ChronicMaleMiddle AgedPandemicsPneumonia, ViralRespiration, ArtificialRisk Factors

Identifiers

PMID32198834
PMCPMC7228209

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.