Evidence map›Paper›PMID 32198800›Full record

ArticleChembiochem : a European journal of chemical biology2020

C-N-Coupled Metabolites Yield Insights into Dynemicin A Biosynthesis.

Douglas R Cohen, Craig A Townsend

Open access · greenAbstract read
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. A discrete intermediate for the biosynthesis of both the enediyne core and the anthraquinone moiety of enediyne natural products.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Douglas R CohenDepartment of Chemistry, The Johns Hopkins University, 3400 North Charles Street, Baltimore, MD, 21218, USA.ORCID 0000-0002-7625-714X
Craig A TownsendDepartment of Chemistry, The Johns Hopkins University, 3400 North Charles Street, Baltimore, MD, 21218, USA.ORCID 0000-0003-2795-7585
Johns Hopkins University · US

Funding

Iterative Polyketide Synthase Function, Structure and PathwaysR01ES001670 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI TOWNSEND, CRAIG ARTHUR · 1985 to 2023
$9.2M
The Chemistry-Biology Interface Program at Johns Hopkins UniversityT32GM080189 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI ROKITA, STEVEN E · 2008 to 2022
$3.5M
NIEHS NIH HHS R01 ES001670NIGMS NIH HHS T32 GM080189
6 · The paper itself

Abstract

The biosynthesis of the three structural subclasses of enediyne antitumor antibiotics remains largely unknown beyond a common C

Indexed as

AnthraquinonesEnediynesMicromonosporaMultigene FamilyMutationAnthraquinonesdynemicin AEnediynesbiosynthesisdynemicinenediyneoxidoreductasespolyketides

Identifiers

PMID32198800
PMCPMC7685002
OpenAlexW3011719546

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.