Evidence map›Paper›PMID 32198647›Full record

ReviewCurrent diabetes reports2020

"H" for Heterogeneity in the Algorithm for Type 2 Diabetes Management.

Pieralice Silvia, Zampetti Simona, Maddaloni Ernesto, Buzzetti Raffaella

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Current diabetes reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Observational
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Pieralice SilviaDepartment of Medicine, Unit of Endocrinology and Diabetes, Campus Bio-Medico University of Rome, Via Alvaro del Portillo 21, 00128, Rome, Italy.
Zampetti SimonaDepartment of Experimental Medicine, Sapienza University, Viale Regina Elena 324, 00161, Rome, Italy.
Maddaloni ErnestoDepartment of Experimental Medicine, Sapienza University, Viale Regina Elena 324, 00161, Rome, Italy. ernesto.maddaloni@uniroma1.it.
Buzzetti RaffaellaDepartment of Experimental Medicine, Sapienza University, Viale Regina Elena 324, 00161, Rome, Italy.
Sapienza University of Rome · ITUniversità Campus Bio-Medico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewGenetic, socioeconomic and clinical features vary considerably among individuals with type 2 diabetes (T2D) influencing disease development, progression and response to therapy. Although a patient-centred approach to pharmacologic therapy of T2D is widely recommended, patients are often treated similarly, irrespective of the differences that may affect therapeutic response. Addressing the heterogeneity of T2D is a major task of diabetes research to lower the high rate of treatment failure as well as to reduce the risk of long-term complications. RECENT

findingsA pathophysiology-based clustering system seems the most promising to help in the stratification of diabetes in terms of complication risk and response to treatment. This urges for clinical studies looking at novel biomarkers related to the different metabolic pathways of T2D and able to inform about the therapeutic cluster of each patient. Here, we review the main settings of diabetes heterogeneity, to what extent it has been already addressed and the current gaps in knowledge towards a personalized therapeutic approach that considers the distinctive features of each patient.

Indexed as

Precision MedicineAlgorithmsBiomarkersDiabetes ComplicationsDiabetes Mellitus, Type 2HumansPatient-Centered CareRisk AssessmentBiomarkersDiabetesHeterogeneityHypoglycemic drugsTherapeutic algorithmType 2 diabetes

Identifiers

PMID32198647
OpenAlexW3011936912

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.