Evidence map›Paper›PMID 32198613›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2020

Imaging angiogenesis in patients with head and neck squamous cell carcinomas by [

D Lobeek, M Rijpkema, S Y A Terry, J D M Molkenboer-Kuenen, L Joosten, E A J van Genugten, A C H van Engen-van Grunsven, J H A M Kaanders, S A H Pegge, O C Boerman and 6 more

Open access · hybridAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
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  4. EGFR- and Integrin αInternational journal of molecular sciences · 2024
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  5. A comparison of [European journal of nuclear medicine and molecular imaging · 2024
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  6. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 3 countries.

D LobeekDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands. daphne.lobeek@radboudumc.nl.
M RijpkemaDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
S Y A TerryDepartment of Imaging Chemistry and Biology, King's College London, London, UK.
J D M Molkenboer-KuenenDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
L JoostenDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
E A J van GenugtenDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
A C H van Engen-van GrunsvenDepartment of Pathology, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands.
J H A M KaandersDepartment of Radiotherapy, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands.
S A H PeggeDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
O C BoermanDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
W L J WeijsDepartment of Oral and Maxillofacial Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.
M A W MerkxDepartment of Oral and Maxillofacial Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.
C M L van HerpenDepartment of Medical Oncology, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands.
R P TakesDepartment of Otolaryngology/Head and Neck Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.
E H J G AarntzenDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
W J G OyenDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
Radboud University Nijmegen · NLRadboud University Medical Center · NLKing's College London · GBRijnstate Hospital · NLUniversity of Twente · NL

Funding

Engineering and Physical Sciences Research Council NoneWellcome Trust WT 203148/Z/16/ZZonMw 95104005
6 · The paper itself

Abstract

purposeAngiogenesis plays an important role in the growth and metastatic spread of solid tumours and is characterised by the expression of integrins on the cell surface of endothelial cells. Radiolabelled RGD peptides specifically target angiogenesis-related α

methodsTen patients with OSCC and scheduled for surgical resection including elective neck dissection received an intravenously administration of

results

conclusions

trial registrationhttps://eudract.ema.europa.eu no. 2015-000917-31.

Indexed as

Carcinoma, Squamous CellHead and Neck NeoplasmsMouth NeoplasmsEndothelial CellsGallium RadioisotopesHumansIntegrin alphaVbeta3Positron Emission Tomography Computed TomographySquamous Cell Carcinoma of Head and NeckTumor MicroenvironmentGallium RadioisotopesIntegrin alphaVbeta3AngiogenesisHead and neck cancerRGD-PET/CTSquamous cell carcinomaαvβ3 integrin

Identifiers

PMID32198613
PMCPMC7515959
OpenAlexW3011910581

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.