Evidence map›Paper›PMID 32198574›Full record

ArticleAMB Express2020

Anserine and glucosamine supplementation attenuates the levels of inflammatory markers in rats with rheumatoid arthritis.

Jiang Minghao Zhao, Xiang Chen, Ke Cheng, Qingming Shi, Kun Peng

Open access · goldAbstract read
In one paragraph

Article in AMB Express, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
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  9. Anserine and Carnosine Induce HSP70-Dependent HAntioxidants (Basel, Switzerland) · 2022
    Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jiang Minghao ZhaoDepartment of Orthopaedics, The Second Affiliated Hospital of Nanchang University, No 1 Minde Road, Donghu District, Nanchang City, 330000, JiangXi Province, China.
Xiang ChenDepartment of Orthopaedics, The Second Affiliated Hospital of Nanchang University, No 1 Minde Road, Donghu District, Nanchang City, 330000, JiangXi Province, China.
Ke ChengDepartment of Orthopaedics, The Second Affiliated Hospital of Nanchang University, No 1 Minde Road, Donghu District, Nanchang City, 330000, JiangXi Province, China.
Qingming ShiDepartment of Orthopaedics, The Second Affiliated Hospital of Nanchang University, No 1 Minde Road, Donghu District, Nanchang City, 330000, JiangXi Province, China. KarynRiveradfc@yahoo.com.
Kun PengDepartment of Orthopaedics, The Second Affiliated Hospital of Nanchang University, No 1 Minde Road, Donghu District, Nanchang City, 330000, JiangXi Province, China. soygwz@163.com.
Second Affiliated Hospital of Nanchang University · CNNanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is an autoimmune disorder that affects the joint synovium. Anserine is a functional dipeptide containing methylhistidine and β-alanine, and is present in the brain and skeletal muscle of birds and mammals. Glucosamine is an amino sugar used in the synthesis of glycosylated proteins and lipids. We evaluated the effects of anserine and glucosamine on RA. Rats were assigned into the control group, RA group, anserine group (1 mg/kg), glucosamine group (200 mg/kg), or anserine plus glucosamine group (anserine, 1 mg/kg + glucosamine, 200 mg/kg). Treatment was continued for 45 consecutive days and was administered orally. The serum levels of catalase, glutathione peroxidase (Gpx), superoxide dismutase (SOD), reduced glutathione (GSH), lipid peroxidation, uric acid, nitric oxide, ceruloplasmin, zinc, copper, prostaglandin E

Indexed as

AnserineAntioxidantGlucosamineRatsRheumatoid arthritis

Identifiers

PMID32198574
PMCPMC7083984
OpenAlexW3012617649

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.