Evidence map›Paper›PMID 32198310›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2020

Confirmation of

Daniela D Maltais, Lennon G Jordan, Hoon-Ki Min, Toji Miyagawa, Scott A Przybelski, Timothy G Lesnick, Robert R Reichard, Dennis W Dickson, Melissa E Murray, Kejal Kantarci and 2 more

Registry-linked trialAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01453127 (DaTSCAN Imaging in Aging and Neurodegenerative Disease), which is not on this map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01453127 phase4enrolling by invitationnot on this map

DaTSCAN Imaging in Aging and Neurodegenerative Disease

TypeinterventionalSponsorMayo ClinicRan2011 to 2026Enrolled500ConditionsDementia, Parkinsonism, Mild Cognitive Impairment, REM Sleep Behavior DisorderArmsI-123 Ioflupane solution injection prior to SPECT scan (DaTscan), Single photon emission computed tomography (SPECT) scan
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Heterogeneity of dementia with lewy bodies: Insights from clinical presentations, neuropathology, and biomarkers.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
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  15. Article
  16. Article
  17. Article
  18. The value of multimodal imaging withNeurobiology of aging · 2021
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Daniela D MaltaisDepartment of Radiology, Mayo Clinic, Rochester, Minnesota.
Lennon G JordanDepartment of Radiology, Mayo Clinic, Rochester, Minnesota.
Hoon-Ki MinDepartment of Radiology, Mayo Clinic, Rochester, Minnesota.
Toji MiyagawaDepartment of Neurology, Mayo Clinic, Rochester, Minnesota.
Scott A PrzybelskiDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
Timothy G LesnickDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
Robert R ReichardDepartment of Anatomic Pathology, Mayo Clinic, Rochester, Minnesota; and.
Dennis W DicksonDepartment of Neuroscience, Mayo Clinic, Jacksonville, Florida.
Melissa E MurrayDepartment of Neuroscience, Mayo Clinic, Jacksonville, Florida.
Kejal KantarciDepartment of Radiology, Mayo Clinic, Rochester, Minnesota.
Bradley F BoeveDepartment of Neurology, Mayo Clinic, Rochester, Minnesota.
Val J LoweDepartment of Radiology, Mayo Clinic, Rochester, Minnesota vlowe@mayo.edu.

Funding

THE PGRN/TDP-43 AXIS IN ALZHEIMER?S DISEASE AND NEURODEGENERATIONP50AG016574 · NIA · MAYO CLINIC ROCHESTER · PI PETERSEN, RONALD C · 1999 to 2018
$36.9M
Research Education ComponentP30AG062677 · NIA · MAYO CLINIC ROCHESTER · PI DENNIS WILLIAM DICKSON · 2019 to 2026
$33.5M
Longitudinal Imaging Biomarkers of Prodromal DLBU01NS100620 · NINDS · MAYO CLINIC ROCHESTER · PI Bradley F Boeve, KEJAL KANTARCI · 2017 to 2026
$19.2M
TRAINING IN TRANSLATIONAL RESEARCH: BENCH TO BEDSIDER25GM055252 · NIGMS · MAYO CLINIC ROCHESTER · PI LUJAN, LUIS, MAHER, LOUIS JAMES · 1996 to 2022
$8.3M
Mayo Clinic Interdisciplinary Women's Health Research ProgramK12HD065987 · NICHD · MAYO CLINIC ROCHESTER · PI KANTARCI, KEJAL · 2010 to 2023
$6.7M
Post-baccalaureate Training in Biomedical ResearchR25GM075148 · NIGMS · MAYO CLINIC ROCHESTER · PI LUJAN, LUIS, MAHER, LOUIS JAMES · 2006 to 2024
$6.1M
NIA NIH HHS P30 AG062677NIA NIH HHS P50 AG016574NICHD NIH HHS K12 HD065987NIGMS NIH HHS R25 GM055252NIGMS NIH HHS R25 GM075148NINDS NIH HHS U01 NS100620
6 · The paper itself

Abstract

Our rationale was to conduct a retrospective study comparing 3

Indexed as

Iodine RadioisotopesTropanesAgedAged, 80 and overAlzheimer DiseaseCorpus StriatumFemaleHumansLewy Body DiseaseMaleMiddle AgedParkinson DiseaseRetrospective StudiesTomography, Emission-Computed, Single-Photon2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropaneIodine RadioisotopesTropanes123I-FP-CIT SPECT123I-ioflupanedementia with Lewy bodiesLewy body diseaseneuropathology

Identifiers

PMID32198310
PMCPMC9364894

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.