Evidence map›Paper›PMID 32198079›Full record

ArticleJournal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus2020

Improved monitoring of adherence with patching treatment using a microsensor and Eye Patch Assistant.

Jingyun Wang, Hongxin Xu, Bryan De La Cruz, Sarah E Morale, Reed M Jost, David A Leske, Jonathan M Holmes, Eileen E Birch

Open access · greenAbstract read
In one paragraph

Article in Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Interventions for improving adherence to amblyopia treatments in children.The Cochrane database of systematic reviews · 2025
    Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jingyun WangSalus University Pennsylvania College of Optometry, Elkins Park, Pennsylvania. Electronic address: jingyun.wang@gmail.com.
Hongxin XuPanorama Windows Ltd. New York, New York.
Bryan De La CruzRetina Foundation of the Southwest, Dallas, Texas.
Sarah E MoraleRetina Foundation of the Southwest, Dallas, Texas.
Reed M JostRetina Foundation of the Southwest, Dallas, Texas.
David A LeskeDepartment of Ophthalmology, Mayo Clinic, Rochester, Minnesota.
Jonathan M HolmesDepartment of Ophthalmology, Mayo Clinic, Rochester, Minnesota.
Eileen E BirchRetina Foundation of the Southwest, Dallas, Texas.
Retina Foundation of the Southwest · USMayo Clinic · USPanorama Research (United States) · USSalus University · US

Funding

Pediatric Eye Disease Investigator Group Coordinating CenterU10EY011751 · NEI · JAEB CENTER FOR HEALTH RESEARCH, INC. · PI KRAKER, RAYMOND · 1997 to 2018
$75.2M
Pediatric Eye Disease Investigator Group NetworkUG1EY011751 · NEI · JAEB CENTER FOR HEALTH RESEARCH, INC. · PI Raymond Kraker, Stacy Pineles · 2019 to 2026
$53.7M
Binocular Vision, Amblyopia, and Refractive Development in EsotropiaR01EY022313 · NEI · RETINA FOUNDATION OF THE SOUTHWEST · PI Eileen Elizabeth Birch · 2012 to 2026
$7.0M
Outcome Measures for Clinical Trials in Pediatric Eye Care and StrabismusR01EY024333 · NEI · MAYO CLINIC ROCHESTER · PI FAUTSCH, MICHAEL P. · 2014 to 2018
$3.3M
Efficacy of Intermittent Occlusion in Amblyopia TreatmentR21EY026664 · NEI · SALUS UNIVERSITY · PI NEELY, DANIEL, WANG, JINGYUN · 2016 to 2017
$394k
NEI NIH HHS R01 EY022313NEI NIH HHS R01 EY024333NEI NIH HHS R21 EY026664NEI NIH HHS U10 EY011751NEI NIH HHS UG1 EY011751
6 · The paper itself

Abstract

backgroundUse of a microsensor has been suggested to monitor patching adherence. Application has been limited because the microsensor's small size makes it easy to lose and a swallowing risk. We designed the Eye Patch Assistant (EPA) to hold the small microsensor in place and reduce the risk of loss or swallowing. This study reports the accuracy, precision, ease of use, and comfort for patching with EPA (patch+EPA) to monitor adherence.

methodsAdults (N = 13) wore an adhesive patch alone or a patch+EPA for 2 hours each, recorded wear time, and completed an ease of use/comfort questionnaire; 30 children wore a patch or patch+EPA and completed the questionnaire. Sensor sampling interval was every 5 minutes or every 1 minute. Sensor accuracy and precision were evaluated by Bland-Altman analysis and 95% limits of agreement, and questionnaire scores compared by Wilcoxon tests.

resultsWith 5-minute sampling, we found excellent accuracy for adults (mean actual vs recorded time difference, 1.4 minutes) and children (mean difference, -0.9 min). We found high precision for both adults and children (95% limits of agreement half widths of 6.4 minutes and 1.9 minutes, respectively). In adults, the ease of use score for the patch+EPA was lower than the patch (P < 0.01), but the comfort score for the patch+EPA was higher (P < 0.01). For children, scores did not differ significantly. The patch+EPA functioned well between 45° and 82°F.

conclusionsThe patch+EPA was well accepted and monitored adherence accurately and precisely.

Indexed as

BandagesEyeHumansMonitoring, PhysiologicSurveys and Questionnaires

Identifiers

PMID32198079
PMCPMC7276289
OpenAlexW3011557983

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.