Evidence map›Paper›PMID 32197971›Full record

ArticleThe Journal of allergy and clinical immunology2020

Obesity may enhance the adverse effects of NO

Perdita Permaul, Jonathan M Gaffin, Carter R Petty, Sachin N Baxi, Peggy S Lai, William J Sheehan, Carlos A Camargo, Diane R Gold, Wanda Phipatanakul

Open access · greenAbstract read
In one paragraph

Article in The Journal of allergy and clinical immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Review
  3. Obesity: Next game changer of allergic airway diseases?Clinical and translational medicine · 2025
    Review
  4. Review
  5. The Impact of the Indoor Environment on Childhood Asthma.Current allergy and asthma reports · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Asthma and Chronic Obstructive Pulmonary Disease.Clinics in chest medicine · 2023
    Review
  14. Article
  15. Article
  16. Environmental Exposures Impact Pediatric Asthma Within the School Environment.Immunology and allergy clinics of North America · 2022
    Review
  17. Obesity-related asthma in children and adolescents.The Lancet. Child & adolescent health · 2022
    Review
  18. Asthma interactions between obesity and other risk factors.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2022
    Review
  19. Article
  20. Asthma Phenotype with Metabolic Dysfunction.Yonsei medical journal · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Perdita PermaulDivision of Pediatric Pulmonology, Allergy and Immunology, New York-Presbyterian/Weill Cornell Medicine, New York, NY; Weill Cornell Medical College, New York, NY.
Jonathan M GaffinDivision of Pulmonary Medicine, Boston Children's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass.
Carter R PettyClinical Research Center, Boston Children's Hospital, Boston, Mass.
Sachin N BaxiDivision of Allergy and Immunology, Boston Children's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass.
Peggy S LaiHarvard Medical School, Boston, Mass; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Mass; Division of Pulmonary and Critical Care, Massachusetts General Hospital, Boston, Mass.
William J SheehanDivision of Allergy and Immunology, Children's National Health System, Washington, DC; George Washington University School of Medicine, Washington, DC.
Carlos A CamargoHarvard Medical School, Boston, Mass; Department of Emergency Medicine, Massachusetts General Hospital, Boston, Mass.
Diane R GoldDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Mass; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Mass.
Wanda PhipatanakulDivision of Allergy and Immunology, Boston Children's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass. Electronic address: wanda.phipatanakul@childrens.harvard.edu.
Boston Children's Hospital · USHarvard University · USBrigham and Women's Hospital · USChildren's National · USCornell University · US

Funding

Harvard Clinical and Translational Science CenterUL1TR001102 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$106.2M
SICAS- Diversity SupplementU01AI110397 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2015 to 2020
$8.8M
ALLERGENS IN INNER-CITY SCHOOLS AND CHILDHOOD ASTHMAR01AI073964 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2008 to 2012
$4.6M
The school microbiome and asthma morbidity in inner-city childrenR01AI144119 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI LAI, PEGGY SUE · 2019 to 2023
$3.7M
Indoor Air Quality and Respiratory Morbidity in School-Aged Children with Bronchopulmonary DysplasiaR01ES030100 · NIEHS · BOSTON CHILDREN'S HOSPITAL · PI GAFFIN, JONATHAN MARK · 2019 to 2023
$3.7M
Environmental Risk Factors for Pediatric Sleep Disordered BreathingR01HL137192 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2017 to 2020
$3.5M
Midcareer Investigator Award: Urban School Allergen Exposures and Childhood AsthmK24AI106822 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2013 to 2022
$1.9M
Atopy, Leptin and Potential Biomarkers of Comorbid Obesity and Asthma in Inner-City SchoolchildrenK23AI123517 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI PERMAUL, PERDITA · 2017 to 2021
$1.1M
Role of Peanut Allergen in Urban Schools and PreschoolsK23AI104780 · NIAID · CHILDREN'S RESEARCH INSTITUTE · PI SHEEHAN, WILLIAM JAMES · 2014 to 2018
$912k
School-based air pollution and asthma morbidity in Inner City School ChildrenK23AI106945 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI GAFFIN, JONATHAN MARK · 2013 to 2017
$822k
NCATS NIH HHS UL1 TR001102NHLBI NIH HHS R01 HL137192NIAID NIH HHS K23 AI104780NIAID NIH HHS K23 AI106945NIAID NIH HHS K23 AI123517NIAID NIH HHS K24 AI106822NIAID NIH HHS L40 AI107923NIAID NIH HHS L40 AI113791NIAID NIH HHS R01 AI073964NIAID NIH HHS R01 AI144119NIAID NIH HHS U01 AI110397NIEHS NIH HHS R01 ES030100
6 · The paper itself

Abstract

backgroundSparse data address the effects of nitrogen dioxide (NO

objectiveWe sought to evaluate relationships between classroom NO

methodsThe School Inner-City Asthma Study enrolled students aged 4 to 13 years with asthma from 37 inner-city schools. Students had baseline determination of BMI percentile. Asthma symptoms, morbidity, pulmonary inflammation, and lung function were monitored throughout the subsequent academic year. Classroom NO

resultsA total of 271 predominantly black (35%) or Hispanic students (35%) were included in analyses. Fifty percent were normal weight (5-84th BMI percentile), 15% overweight (≥85-94th BMI percentile), and 35% obese (≥95th BMI percentile). For each 10-parts per billion increase in NO

conclusionsObese BMI status appears to increase susceptibility to classroom NO

Indexed as

AdolescentAir Pollution, IndoorAsthmaBody Mass IndexChildChild, PreschoolEnvironmental ExposureFemaleHumansMaleMorbidityNitrogen DioxideObesityPrognosisSchoolsUrban PopulationNitrogen DioxideairAsthmaBMIbody mass indexchildrenenvironmentexposureindoorinner-citynitrogen dioxideNO(2)obesitypollutantschoolurban

Identifiers

PMID32197971
PMCPMC7501199
OpenAlexW3010727504

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.